ARCH Venture Partners

Venture Capital

Deep Science & Academic Spinouts

Chicago, United States · 234+ investments · 176 portfolio companies

Seed
Early Stage
Deep Tech
Headquarters
Chicago, United States
AUM
$9.4B
Portfolio Companies
176
Total Investments
234
Last Investment
Sep 2026
Geographic Focus
United States

Indexed holds 176 portfolio companies and 234 funding rounds for this investor. The full record is or through the API.

Investment Thesis

Co-founds and backs deep science companies at the earliest stages, partnering directly with university researchers and scientists to commercialize breakthrough discoveries in life sciences, biotech, and deep tech.

ARCH Venture Partners is a Venture Capital firm based in Chicago, United States. It has made 234 investments, including Moleculent AB, ImmuneID and Salma Health. Focus areas include Deep Tech.

Portfolio176

Showing 48 of 176 recorded portfolio companies.

Moleculent AB
ImmuneID
Salma Health
GRAIL
Twist Bioscience
Walden Biosciences
Rippl
Magnet Biomedicine
MedVantx
Karuna Therapeutics
Syneron Bio
L1 AgroSciences
Sironax
Bitterroot Bio
Crystal IS
Lightcast Discovery
JT
Juno Therapeutics
Encoded Therapeutics
Rome Therapeutics
Matter Neuroscience
Gate Bioscience
Parabilis Medicines
Orbital Therapeutics
Quantum Circuits
Lilac Therapeutics
Cytrellis Biosystems
GS Holdings (formerly Genuity Science (WuXi Nextcode Genomics – Fjord))
Genomics Medicine Ireland
Dewpoint Therapeutics
Siluria
Carrick Therapeutics
5Metis
Lifordi Immunotherapeutics
Illumina
nChroma Bio
Agrivida
SonoThera
Oratomic
BE Biopharma
Pulmatrix
City Therapeutics
RhyGaze
Anchordx
eGenesis
Areteia Therapeutics
VP
Ventirx Pharmaceuticals
Trase
Atlas Data Storage

Co-investors24

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24 co-investors across 299 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×21 · Corporate VC ×1 · Other ×1 · 238 shared rounds

Investment History

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ARCH Venture Partners on Indexed.vc
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