Pretzel Therapeutics
A New Paradigm In Cellular Energetics
Waltham, United States · Founded 2022 · $131.8M raised
- Headquarters
- Waltham, Massachusetts
- Employees
- 11–50
- Founded
- 2022
- Business Model
- B2B
- Website
- pretzeltx.com
- Total Funding
- $131.8M
- Last Round
- $59.3M Venture RoundAug 2024
- Rounds
- 2
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
About
Pretzel Therapeutics is a clinical-stage biotech company developing small molecule therapies that target mitochondrial biology to treat metabolic diseases, rare mitochondrial disorders, and aging-related conditions. The company's lead program PX578 entered Phase 1 clinical trials in 2025, targeting POLRMT as a novel mechanism for metabolic disease treatment. Pretzel collaborates with leading research institutions including SciLifeLab to advance mitochondrial drug discovery.
Summary
Pretzel Therapeutics is a Biotech company based in Waltham, United States, founded in 2022. It has raised $131.8M in total across 2 rounds, most recently a $59.3M Venture Round in Aug 2024. Investors include ARCH Venture Partners, Mubadala Capital and HealthCap.
Tech & App Stack
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Funding History
Aug 2024
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Funding: Venture Round. Amounts, valuations, and investors where available.
Investors
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