
Pretzel Therapeutics
Waltham, United States · Founded 2022 · $131.8M raised
- Headquarters
- Waltham, Massachusetts
- Employees
- 11–50
- Founded
- 2022
- Business Model
- B2B
- Website
- pretzeltx.com
- Total Funding
- $131.8M
- Last Round
- $59.3M Venture RoundAug 2024
- Rounds
- 2
About
Pretzel Therapeutics is a clinical-stage biotech company developing small molecule therapies that target mitochondrial biology to treat metabolic diseases, rare mitochondrial disorders, and aging-related conditions. The company's lead program PX578 entered Phase 1 clinical trials in 2025, targeting POLRMT as a novel mechanism for metabolic disease treatment. Pretzel collaborates with leading research institutions including SciLifeLab to advance mitochondrial drug discovery.
Summary
Pretzel Therapeutics is a Biotech company based in Waltham, United States, founded in 2022. It has raised $131.8M in total across 2 rounds, most recently a $59.3M Venture Round round in Aug 2024. Investors include ARCH Venture Partners, Mubadala Capital and HealthCap.
Tech & App Stack
4 technologies & apps tracked
Create a free account — 10 credits a month to unlock the full tech & app stack, funding history, and valuations.
Sign up to view the funding chart
Create a free account — you'll get 10 credits a month to unlock funding history, valuations, and tech stacks.
Funding History
Aug 2024
Sign up to see all 2 rounds
Full funding history, per-round amounts, and investor participation.
Investors
Similar Companies

Clinical-stage precision medicine company developing targeted therapies for immune-mediated infla...

China's leading mRNA biotech company developing therapeutics for cancer and infectious diseases.
Biopharmaceutical company developing and commercializing RNAi therapeutics to treat genetically d...

Develops Gene Writing technology and non-viral delivery to create in vivo genetic medicines for m...

San Diego-based clinical stage biopharmaceutical company focused on the development of small mole...

Clinical-stage biopharmaceutical developing precision medicines targeting novel mechanisms to tre...
