Denali Therapeutics

IPO

Transforming Life

Public · South San Francisco, United States · Founded 2015 · $1.3B raised

Employees
201–500
Founded
2015
Business Model
B2B
Total Funding
$1.3B
Last Round
$200.0M Venture RoundDec 2025
Rounds
5
Type
Public

About

Denali Therapeutics is a clinical-stage biotechnology company that invented the TransportVehicle™ platform, enabling biotherapeutics to cross the blood-brain barrier and treat neurodegenerative, lysosomal storage, and other serious diseases. With a clinically validated delivery platform, Denali is advancing a broad pipeline of investigational medicines in collaboration with partners including Biogen and Takeda.

Summary

Denali Therapeutics is a Biotech company based in South San Francisco, United States, founded in 2015. It has raised $1.3B in total across 5 rounds, most recently a $200.0M Venture Round round in Dec 2025. Investors include Royalty Pharma, Baillie Gifford and Redmile Group.

Tech & App Stack

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Funding History

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Venture RoundVenture RoundDec 2025
$200.0M

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Venture Round — per-round amounts, valuations, and who invested in each round.

Investors

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