City Therapeutics
Engineering the future of RNAi-based medicine
Cambridge, United States · Founded 2024 · $234.5M raised
- Headquarters
- Cambridge, Massachusetts
- Founded
- 2024
- Business Model
- B2B
- Website
- citytx.com
- Total Funding
- $234.5M
- Last Round
- $99.5M Series BJun 2026
- Rounds
- 2
About
City Therapeutics is a Cambridge, MA-based clinical-stage biopharmaceutical company founded by RNAi pioneers to engineer next-generation small interfering RNA (siRNA) therapeutics. Its platform advances novel trigger molecules and extrahepatic delivery ligands to expand RNAi reach beyond the liver. Lead programs include CITY-FXI for thromboembolic diseases and CITY-RBP4 for Stargardt disease, backed by over $230 million in financing.
Summary
City Therapeutics is a Biotech company based in Cambridge, United States, founded in 2024. It has raised $234.5M in total across 2 rounds, most recently a $99.5M Series B round in Jun 2026. Investors include Viking Global, ARCH Venture Partners and Sofinnova Investments.
Tech & App Stack
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Funding History
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Jun 2026
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Series A through Series B — per-round amounts, valuations, and who invested in each round.
Investors
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