City Therapeutics

Engineering the future of RNAi-based medicine

Cambridge, United States · Founded 2024 · $234.5M raised

Employees
51–200
Founded
2024
Business Model
B2B
Website
citytx.com
Total Funding
$234.5M
Last Round
$99.5M Series BJun 2026
Rounds
2

Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.

About

City Therapeutics is a Cambridge, MA-based clinical-stage biopharmaceutical company founded by RNAi pioneers to engineer next-generation small interfering RNA (siRNA) therapeutics. Its platform advances novel trigger molecules and extrahepatic delivery ligands to expand RNAi reach beyond the liver. Lead programs include CITY-FXI for thromboembolic diseases and CITY-RBP4 for Stargardt disease, backed by over $230 million in financing.

Summary

City Therapeutics is a Biotech company based in Cambridge, United States, founded in 2024. It has raised $234.5M in total across 2 rounds, most recently a $99.5M Series B round in Jun 2026. Investors include Viking Global, ARCH Venture Partners and Sofinnova Investments.

Tech & App Stack

2 technologies & apps tracked

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Funding History

Series BSeries BJun 2026
$99.5M

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Funding: Series A through Series B. Amounts, valuations, and investors where available.

Investors

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