Seaport Therapeutics

Boston, United States · Founded 2024 · $340.0M raised

Employees
11–50
Founded
2024
Total Funding
$340.0M
Last Round
$15.0M GrantMar 2026
Rounds
3

About

Seaport Therapeutics is a clinical-stage biopharmaceutical company advancing novel neuropsychiatric medicines in areas of high unmet patient need, including depression, anxiety, and other CNS disorders. Founded in Boston in 2024 by Daphne Zohar (Founder & CEO) and Steven M. Paul, M.D. (Founder & Board Chair) - the team behind Karuna Therapeutics' KarXT - the company pairs clinically validated mechanisms with its proprietary Glyph technology platform, which uses the lymphatic system to enable oral bioavailability and reduce side effects like hepatotoxicity. Backed by ARCH Venture Partners, Sofinnova Investments, Third Rock Ventures, and PureTech Health, Seaport completed its Nasdaq IPO (SPTX) in April 2026.

Summary

Seaport Therapeutics is a Life Sciences company based in Boston, United States, founded in 2024. It has raised $340.0M in total across 3 rounds, most recently a $15.0M Grant round in Mar 2026. Investors include General Atlantic, ARCH Venture Partners and Sofinnova Investments.

Tech & App Stack

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Funding History

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GrantMar 2026
$15.0M

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Series A through Grant — per-round amounts, valuations, and who invested in each round.

Investors

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