All Rankings

Top 100 Biotech Startups in Boston 2026

The most-funded biotechnology and genomics startups headquartered in Boston and Cambridge, Massachusetts, ranked by total capital raised.

Known total funding for 100 of 100 ranked companies: $19.2B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?industries=Biotech,Genomics&countries=United+States&cities=Boston,Cambridge&states=Massachusetts&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API state filter leaves out companies with no recorded state; this list keeps them when the city matches.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant, private equity or debt financing; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant, Private Equity, Debt Financing are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

1
Lila Sciences

Lila Sciences combines artificial intelligence with autonomous laboratories to accelerate scienti...

Cambridge, United States51–200Artificial Intelligence, Biotech
Series ATotal funding$1.3BJun 2026
2
Beeline Medicines

Beeline Medicines is a clinical-stage biotechnology company developing precision therapies for pe...

Boston, United States11–50Biotech, Healthcare
Series ATotal funding$852.6MJul 2026
3
FogPharma

Biopharmaceutical company pioneering Helicon peptide drugs to target previously undruggable prote...

Cambridge, United States51–200Biotech, Drug Discovery
Series FTotal funding$801.0MJan 2025
4
Aviceda

World leader in glyco-immune checkpoint therapeutics developing immune-mediated therapies for pat...

Cambridge, United States51–200Biotech, Healthcare
Series CTotal funding$572.6MJan 2025
5
Nimbus Therapeutics

Nimbus Therapeutics is a clinical-stage biotech developing novel small molecule medicines using s...

Cambridge, United States51–200Biotech, Healthcare
Growth EquityTotal funding$572.0MSep 2023
6
nChroma Bio

Genetic medicines company developing targeted in vivo delivery and engineered epigenetic silencer...

Boston, United States51–200Biotech, Genomics
Venture RoundTotal funding$470.0MDec 2024
7
eGenesis

eGenesis engineers human-compatible donor organs using multiplex gene editing to advance cross-sp...

Cambridge, United States51–200Biotech, Healthcare
Series DTotal funding$416.0MSep 2024
8
Inari Agriculture

AgTech company using AI-enabled predictive design and multiplex gene editing to create superior s...

Cambridge, United States201–500Biotech
Series G+Total funding$357.0MJan 2024
9
BE Biopharma

Biotech company pioneering Engineered B Cell Medicines (BCMs) to treat genetic diseases like Hemo...

Cambridge, United States51–200Biotech, Healthcare
Series CTotal funding$356.0MJan 2025
10
Dewpoint Therapeutics

Biotech company applying biomolecular condensate science to drug discovery across oncology, neuro...

Boston, United States51–200Life Sciences, Biotech
Series DTotal funding$346.1MSep 2025
11
Obsidian Therapeutics

Biotechnology company developing engineered tumor-infiltrating lymphocyte cell therapies to impro...

Cambridge, United States51–200Biotech
Series CTotal funding$325.0MApr 2024
12
Arbor Biotechnologies

Develops next-generation gene editing therapeutics for genetic diseases, advancing liver and CNS ...

Cambridge, United States51–200Biotech, Drug Discovery
Series CTotal funding$304.5MMar 2025
13
Valo Health

AI-enabled biotechnology company using large-scale human data and computation to accelerate drug ...

Boston, United States51–200Artificial Intelligence, Biotech
Series BTotal funding$300.0MMar 2021
14
Flare Therapeutics

Biotech startup developing precision small molecule medicines targeting transcription factors for...

Cambridge, United States11–50Biotech, Healthcare
Series CTotal funding$290.0MJun 2026
15
Repertoire Immune Medicines

Repertoire Immune Medicines is a clinical-stage biotechnology company decoding the human T cell r...

Cambridge, United States51–200Biotech
Venture RoundTotal funding$289.0MApr 2025
16
Mediar Therapeutics

Mediar develops novel fibrosis treatments that disable myofibroblasts, aiming to slow or reverse ...

Cambridge, United States11–50Biotech, Healthcare
Series BTotal funding$282.0MJun 2026
17
Atavistik Bio

Develops selective allosteric therapeutics that modulate disease-causing proteins, aiming to tran...

Cambridge, United States11–50Biotech, Healthcare
Extension RoundTotal funding$265.3MMar 2026
18
Myeloid Therapeutics

Clinical-stage biotech pioneering in vivo multi-immune programming using proprietary mRNA-LNP CAR...

Cambridge, United States11–50Biotech, Therapeutics
Series BTotal funding$257.0MMay 2026
19
Celea Therapeutics

Celea advances deupirfenidone for people with serious respiratory diseases, targeting idiopathic ...

Boston, United States11–50Biotech, Healthcare
Series BTotal funding$255.0MJul 2026
20
PathAI

PathAI develops AI-powered precision pathology solutions that analyze tissue samples, helping pat...

Boston, United States201–500Artificial Intelligence, Biotech
Series CTotal funding$251.0MMay 2021
21
Matchpoint Therapeutics

Matchpoint Therapeutics discovers precision small molecule medicines that use covalent bonding to...

Boston, United States11–50Biotech, Healthcare
Series BTotal funding$250.0MOct 2026
22
Seismic Therapeutic

Clinical-stage immunology biotech using machine learning to design biologic therapeutics for auto...

Cambridge, United States51–200Biotech, Drug Discovery
Extension RoundTotal funding$247.0MJul 2025
23
AIRNA

Clinical-stage biotech pioneering RNA editing therapeutics to repair disease-causing genetic vari...

Cambridge, United States11–50Biotech, Healthcare
Series BTotal funding$245.0MApr 2025
24
ArtBio

Clinical-stage radiopharmaceutical biotech developing alpha radioligand therapies for cancer, fou...

Cambridge, United States11–50Biotech, Healthcare
Series BTotal funding$245.0MJul 2025
25
MOMA Therapeutics

MOMA Therapeutics develops precision medicines by targeting molecular machines that underlie dise...

Cambridge, United States51–200Biotech, Healthcare
Series BTotal funding$236.0MMay 2022