All Rankings

Top Series B Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was Series B, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $59.4B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series B.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

1
Project Prometheus

AI company focused on applying artificial intelligence to physical tasks, launched with $6.2B ini...

San Francisco, United States51–200Artificial Intelligence, Manufacturing
Series BTotal funding$18.2BJun 2026
2
Reflection

Reflection builds open-weight frontier AI models and research tools intended to make advanced int...

San Francisco, United States11–50Artificial Intelligence
Series BTotal funding$2.1BOct 2025
3
Valar Atomics

Nuclear energy startup building hundreds of reactors at one Gigasite for heavy industrial power a...

El Segundo, United States11–50Climate Tech, Defense Tech
Series BTotal funding$1.7BAug 2026
4
Physical Intelligence

Physical Intelligence is building a foundation model for robotics, bringing general-purpose AI in...

San Francisco, United States11–50Artificial Intelligence, Robotics
Series BTotal funding$1.1BNov 2025
5
Forte

Blockchain infrastructure platform enabling game publishers to integrate compliant on-chain econo...

San Francisco, United States201–500Crypto & Web3, Education
Series BTotal funding$910.0MNov 2021
6
DCG

Digital Currency Group is Barry Silbert's crypto conglomerate that builds and invests in bitcoin ...

Stamford, United States51–200Crypto & Web3, Fintech
Series BTotal funding$841.0MNov 2021
7
Automation Anywhere

Automation Anywhere is a software provider of robotic process automation to help global companies...

San Jose, United States1001–5000Artificial Intelligence, Automation
Series BTotal funding$840.0MNov 2019
8
Avenzo

Avenzo is a San Diego, CA-based biopharma company to in-license and develop the next generation o...

San Diego, United States1–10Biotech, Oncology
Series BTotal funding$832.0MSep 2025
9
Poolside

Poolside develops large language models specifically designed for software engineering, providing...

San Francisco, United States51–200Artificial Intelligence, Developer Tools
Series BTotal funding$752.0MOct 2024
10
Reve Image

AI image generation platform trained for prompt adherence, aesthetics, and typography with advanc...

Palo Alto, United States11–50Artificial Intelligence
Series BTotal funding$740.0MNov 2025
11
Higgsfield

Generative AI platform for creators and social media teams to create and edit images, videos, and...

San Francisco, United States51–200Generative AI, Media
Series BTotal funding$718.0MAug 2026
12
EnerVenue

EnerVenue develops enduring energy storage infrastructure using proven nickel-hydrogen chemistry ...

Fremont, United States51–200Clean Energy
Series BTotal funding$700.0MMar 2026
13
Tripo AI

AI 3D and world-model foundation platform.

San Francisco, United States51–200Artificial Intelligence
Series BTotal funding$696.0MSep 2026
14
LiveKindly

Global plant-based food company and collective of heritage brands on a mission to make plant-base...

New York, United States201–500Climate Tech, E-Commerce
Series BTotal funding$670.0MMar 2021
15
Mirador Therapeutics

Clinical-stage precision medicine company developing targeted therapies for immune-mediated infla...

San Diego, United States11–50Biotech, Drug Discovery
Series BTotal funding$650.0MOct 2025
16
Nexthop AI

Nexthop AI develops networking products and infrastructure for hyperscale cloud and AI data cente...

Santa Clara, United States51–200Artificial Intelligence, Developer Tools
Series BTotal funding$610.0MMar 2026
17
MatX

Designs high-throughput AI chips for large language models, serving AI labs and enterprises seeki...

Mountain View, United States11–50Artificial Intelligence, Semiconductors
Series BTotal funding$600.0MFeb 2026
18
Cardurion

Cardurion Pharmaceuticals is a clinical-stage biotechnology company focused on the discovery and ...

Burlington, United States11–50Biotech, Healthcare
Series BTotal funding$560.0MJul 2024
19
Pebl

Pebl allows companies to hire, pay, and manage employees in 185+ countries—removing risk, red tap...

San Francisco, United States501–1000Artificial Intelligence, Fintech
Series BTotal funding$500.0MMay 2022
20
Zyphra

Zyphra runs a research lab pushing the frontier of open intelligence and a full-stack AI cloud pl...

San Francisco, United States11–50Artificial Intelligence
Series BTotal funding$500.0MMay 2026
21
TensorWave

TensorWave provides an AMD-exclusive AI cloud for teams training, fine-tuning, and deploying larg...

Las Vegas, United States51–200Artificial Intelligence, Cloud
Series BTotal funding$493.0MJun 2026
22
Armada

Full-stack edge computing platform providing connectivity, compute, and AI solutions for remote a...

San Francisco, United States201–500Artificial Intelligence, Infrastructure
Series BTotal funding$469.0MMay 2026
23
Age of Learning, Inc.

Leading edtech company developing engaging digital learning resources for children ages 2–8, best...

San Francisco, United States501–1000EdTech, Education
Series BTotal funding$465.0MJun 2021
24
Decart

Decart is a frontier AI lab that builds real-time generative video models and the infrastructure ...

San Francisco, United States51–200Developer Tools, Generative AI
Series BTotal funding$453.0MMay 2026
25
Armadin

AI-native cybersecurity company founded by ex-Mandiant CEO Kevin Mandia, building an autonomous o...

San Francisco, United States11–50Artificial Intelligence, Cybersecurity
Series BTotal funding$445.5MOct 2026