All Rankings

Top 100 Biotech Companies 2026

Private biotechnology and genomics companies, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $65.6B.

Showing top 100 matching companies · Ranked by total funding raised · Latest company record update Oct 3, 2026

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

1
Altos Labs

Altos Labs combines academic science and industry development to create medicines that restore ce...

San Francisco, United States501–1000Life Sciences, Biotech
Series ATotal funding$3.0BJan 2022
2
Isomorphic Labs

AI-first drug discovery company using AlphaFold-derived models to design therapeutics and acceler...

London, United Kingdom201–500Artificial Intelligence, Biotech
Series BTotal funding$2.6BMay 2026
3
Calico

Calico researches human aging using advanced technologies and model systems, applying that knowle...

South San Francisco, United States201–500Biotech, Healthcare
Corporate RoundTotal funding$2.3BJun 2018
4
National Resilience

Contract development and manufacturing organization (CDMO) focused on delivering high-quality bio...

BLUE ASH, United States1001–5000Biotech
Venture RoundTotal funding$2.2BJun 2025
5
Impossible Foods

Food technology company creating plant-based meat and dairy products that replicate the taste and...

Redwood City, United States501–1000Agtech, Biotech
Series G+Total funding$1.9BNov 2021
6
Dren Bio

Dren Bio develops novel antibody therapeutics that selectively deplete pathogenic cells and other...

San Carlos, United States11–50Biotech
Corporate RoundTotal funding$1.8BDec 2025
7
Lila Sciences

Lila Sciences combines artificial intelligence with autonomous laboratories to accelerate scienti...

Cambridge, United States51–200Artificial Intelligence, Biotech
Series ATotal funding$1.3BJun 2026
8
Elevate Bio

ElevateBio is a technology-driven company that partners with innovators to develop transformative...

Waltham, United States201–500Biotech, Healthcare
Series DTotal funding$1.2BMay 2023
9
Neuralink

Neuralink develops investigational implantable brain-computer interfaces that help people with pa...

Fremont, United States201–500Biotech, Healthcare
Series ETotal funding$1.2BJun 2025
10
Abogen Biosciences

Abogen Biosciences develops RNA therapeutics using integrated mRNA design, lipid nanoparticle del...

Suzhou, China201–500Biotech, Drug Discovery
Extension RoundTotal funding$1.2BNov 2021
11
Ultima Genomics

Ultima Genomics develops high-throughput DNA sequencing platforms that use open-wafer technology ...

Fremont, United States201–500Artificial Intelligence, Healthcare
Series ETotal funding$1.1BJun 2022
12
Kailera

Kailera develops therapies for obesity built on GLP-1-based mechanisms, advancing four clinical-s...

Waltham, United States51–200Biotech, Healthcare
Series BTotal funding$1.0BOct 2025
13
Xaira Therapeutics

Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intellig...

South San Francisco, United States51–200Artificial Intelligence, Biotech
Series ATotal funding$1.0BApr 2024
14
ArsenalBio

Clinical-stage programmable cell therapy company developing engineered T-cell therapies for solid...

San Francisco, United States201–500Biotech, Life Sciences
Series CTotal funding$955.0MSep 2024
15
Cellares

Cellares develops and operates automated smart factories that manufacture cell therapies for biot...

South San Francisco, United States51–200Biotech, Healthcare
Series DTotal funding$939.0MJun 2026
16
Apeel Sciences

Apeel Sciences develops plant-based edible coatings that extend the shelf life of fresh produce, ...

GOLETA, United States201–500Agtech, Biotech
Series FTotal funding$912.9MJul 2025
17
NewLimit

NewLimit develops medicines that unlock cellular regenerative potential to extend human healthspa...

South San Francisco, United States11–50Biotech, Healthcare
Venture RoundTotal funding$865.0MJun 2026
18
Element Biosciences

Life science company democratizing access to advanced DNA sequencing tools with high-quality, aff...

San Diego, United States201–500Biotech, Genomics
Series ETotal funding$853.3MJun 2026
19
Avenzo

Avenzo is a San Diego, CA-based biopharma company to in-license and develop the next generation o...

San Diego, United States1–10Biotech, Oncology
Series BTotal funding$832.0MSep 2025
20
Treeline Biosciences

Clinical-stage biopharma developing precision medicines for cancer and other serious diseases usi...

Watertown, United States51–200Biotech, Drug Discovery
Extension RoundTotal funding$821.8MSep 2025
21
Cardurion

Cardurion Pharmaceuticals is a clinical-stage biotechnology company focused on the discovery and ...

Burlington, United States11–50Biotech, Healthcare
Series BTotal funding$820.0MJul 2024
22
LifeMine

Therapeutics company working in drug discovery and development using fungi with genomics approach...

Watertown, United States51–200Biotech, Drug Discovery
Venture RoundTotal funding$816.0MAug 2026
23
Spiber

Spiber develops Brewed Protein materials, using microbial fermentation to create plant-based fibe...

Tokyo, Japan201–500Biotech, Manufacturing
Venture RoundTotal funding$807.6MDec 2024
24
FogPharma

Biopharmaceutical company pioneering Helicon peptide drugs to target previously undruggable prote...

Cambridge, United States51–200Biotech, Drug Discovery
Series FTotal funding$801.0MJan 2025
25
Perfect Day

Sustainable dairy protein from precision fermentation

Berkeley, United States51–200Biotech
Series ETotal funding$787.7MJan 2024