Top Seed-Stage Companies in the US 2026

AI research and product company building customizable, multimodal AI systems.

Months-old startup developing self-teaching AI toward superintelligence.

Stablecoin orchestration infrastructure

Don't let breakdowns break the bank

Human-centric frontier AI research lab building AI models that prioritize coordination, communica...

Building energy-efficient AI compute systems, founded by former Databricks head of AI Naveen Rao

Yuga Labs is a web3 platform building what's next, most known for the creation of the Bored Ape Y...

AI image generation platform trained for prompt adherence, aesthetics, and typography with advanc...

Periodic Labs develops artificial intelligence systems that simulate and predict the properties o...

BitClout (now DeSo) is a layer-1 blockchain built to decentralize social media, enabling creator ...

US-regulated cryptocurrency exchange offering access to digital assets with low trading fees, lic...

AI research lab by former Anthropic researchers helping scientists develop AI.

AI cybersecurity startup

Technology company building end-to-end DNA data storage solutions for long-term archival.

AI inference startup commercializing the open-source vLLM project for high-performance large lang...

AI research lab building frontier protein and genome language models for the life sciences

For people facing ever-widening coverage gaps, Centinel's claims-free coverage for hard-to-insure...

UTokyo IPC life science portfolio company

AI-powered mortgage lender that automates origination to offer lower rates and simpler home buyin...

Helping people establish credit history

AI chip design company.

A compliance training platform built for regulated industries.

Developer tools infrastructure platform for building and deploying applications.

HoneyBee is an HR financial wellness platform helping employers attract and retain talent through...

Agentic AI OS for regulated industries including healthcare and defense.