5AM Ventures

Venture Capital

We invest in seed and early-stage life sciences and biotechnology companies.

Boston, United States · 67+ investments · 78 portfolio companies

Seed
Early Stage
Biotech
Life Sciences
Medical Devices
Headquarters
Boston, United States
Founded
2002
AUM
$1.0B
Portfolio Companies
78
Total Investments
67
Last Investment
Jan 2026
Geographic Focus
United States

Investment Thesis

We invest in seed and early-stage life sciences and biotechnology companies.

5AM Ventures is a Venture Capital firm based in Boston, United States. It has made 67 investments in Biotech and Life Sciences, including Crinetics Pharmaceuticals, Inc., Entrada Therapeutics and Ikaria.

Portfolio78

Co-investors24

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24 co-investors across 118 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×18 · Corporate VC ×3 · Hedge Fund ×2 · 84 shared rounds

Investment History

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