Carmot Therapeutics

Acquired

Developing life-changing therapeutics for metabolic disease

Berkeley, United States · Founded 2008 · $497.0M raised

Employees
11–50
Founded
2008
Business Model
biotech
Total Funding
$497.0M
Last Round
$150.0M Series EMay 2023
Rounds
5

About

Carmot Therapeutics was a clinical-stage biotechnology company dedicated to developing life-changing therapeutics for people living with metabolic diseases including obesity and type 2 diabetes. The company's pipeline included CT-388 (a once-weekly injectable dual GLP-1/GIP receptor agonist), CT-868 (dual GLP-1/GIP receptor agonist in Phase 2 for obesity/T1D), and CT-996 (an oral small molecule GLP-1 receptor agonist). Carmot's drug candidates were designed as biased agonists that activate cAMP signaling with minimal beta-arrestin recruitment, expected to yield prolonged pharmacological activity and strong tolerability. The company was acquired by Roche in January 2024 for $2.7 billion upfront ($3.1 billion total) and is now operated as part of Roche/Genentech's obesity and diabetes pipeline.

Summary

Carmot Therapeutics is a Biotech company based in Berkeley, United States, founded in 2008. It has raised $497.0M in total across 5 rounds, most recently a $150.0M Series E round in May 2023. Investors include Deep Track Capital, The Column Group and Horizons Ventures.

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Funding History

AcquisitionDec 2023
$2.7B

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