Dianthus Therapeutics is a clinical-stage biotechnology company developing next-generation complement-targeted antibody therapies for severe autoimmune and inflammatory diseases. Its lead candidate, claseprubart (DNTH103), is engineered with extended half-life and high selectivity for active C1s complement protein, enabling self-administered subcutaneous injections. A second candidate, DNTH212, is a bifunctional inhibitor targeting Type 1 IFN suppression and B cell modulation.
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Apr 2022
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