All Rankings

Top Series B Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was Series B, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $59.4B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series B.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

76
Nimble Robotics

Nimble operates autonomous fulfillment centers using AI-powered warehouse robots to pick, pack, s...

San Francisco, United States201–500Artificial Intelligence, Logistics
Series BTotal funding$269.0MFeb 2026
77
Harbor Health

Austin-based primary and specialty clinic group that provides integrated care and clinician-desig...

Austin, United States201–500Life Sciences, Healthcare
Series BTotal funding$258.0MSep 2025
78
Myeloid Therapeutics

Clinical-stage biotech pioneering in vivo multi-immune programming using proprietary mRNA-LNP CAR...

Cambridge, United States11–50Biotech, Therapeutics
Series BTotal funding$257.0MMay 2026
79
Genesis Therapeutics

Genesis Therapeutics is an AI drug discovery company using generative AI and physics-based molecu...

Burlingame, United States51–200Artificial Intelligence, Biotech
Series BTotal funding$256.1MAug 2023
80
Genesis Molecular AI

Genesis Molecular AI combines foundation models and drug-discovery expertise to develop small-mol...

Burlingame, United States51–200Artificial Intelligence, Healthcare
Series BTotal funding$256.0MAug 2023
81
Heirloom

Heirloom is restoring balance to our atmosphere by capturing CO2 from the air through engineering...

San Francisco, United States51–200Sustainability, Climate Tech
Series BTotal funding$256.0MDec 2024
82
Articul8 AI

Enterprise generative AI software platform providing secure, domain-specific AI for regulated ind...

Santa Clara, United States51–200Artificial Intelligence, SaaS
Series BTotal funding$255.0MJun 2026
83
Celea Therapeutics

Celea advances deupirfenidone for people with serious respiratory diseases, targeting idiopathic ...

Boston, United States11–50Biotech, Healthcare
Series BTotal funding$255.0MJul 2026
84
Pathalys Pharma

Pathalys Pharma develops advanced therapeutics for people with late-stage chronic kidney disease,...

Raleigh, United States1–10Biotech, Healthcare
Series BTotal funding$255.0MAug 2024
85
Allen Control Systems

Allen Control Systems builds AI-powered autonomous robotic weapon stations for counter-drone defe...

Alexandria, United States11–50Defense Tech
Series BTotal funding$254.0MJun 2026
86
Augment

AI-powered software development platform with an industry-leading context engine that understands...

Palo Alto, United States51–200Artificial Intelligence, Developer Tools
Series BTotal funding$252.0MApr 2024
87
RWDC Industries

RWDC Industries develops biopolymer resin formulations with manufacturing customers, helping them...

Athens, United States51–200Advanced Materials, Biotech
Series BTotal funding$250.1MNov 2021
88
Crete Professionals Alliance

Professional services firm providing tax, advisory, and accounting services through subsidiary en...

Tampa, United States51–200Fintech
Series BTotal funding$250.0MJan 2025
89
Liquid AI

AI model company building efficient neural networks (Liquid Neural Networks) for edge and cloud d...

Cambridge, United States51–200Artificial Intelligence, Developer Tools
Series BTotal funding$250.0MDec 2024
90
Matchpoint Therapeutics

Matchpoint Therapeutics discovers precision small molecule medicines that use covalent bonding to...

Boston, United States11–50Biotech, Healthcare
Series BTotal funding$250.0MOct 2026
91
Syneron Bio

Syneron Bio is a biotech company dedicated to the development of next-generation macrocyclic pept...

Beijing, United States51–200Biotech, Healthcare
Series BTotal funding$250.0MApr 2026
92
Mojo Vision

Mojo Vision is the Invisible Computing Company, dedicated to developing augmented reality product...

Saratoga, United States11–50AR/VR, Artificial Intelligence
Series BTotal funding$248.7MSep 2025
93
AIRNA

Clinical-stage biotech pioneering RNA editing therapeutics to repair disease-causing genetic vari...

Cambridge, United States11–50Biotech, Healthcare
Series BTotal funding$245.0MApr 2025
94
ArtBio

Clinical-stage radiopharmaceutical biotech developing alpha radioligand therapies for cancer, fou...

Cambridge, United States11–50Biotech, Healthcare
Series BTotal funding$245.0MJul 2025
95
Rho

Fintech platform offering business banking, corporate cards, treasury, and expense management for...

New York, United States201–500Banking, Fintech
Series BTotal funding$244.9MAug 2026
96
Blitzy

Blitzy autonomously reverse engineers enterprise codebases, then generates, refactors, and modern...

Cambridge, United States11–50Artificial Intelligence, Developer Tools
Series BTotal funding$244.4MMay 2026
97
Ray Therapeutics

Ray Therapeutics develops optogenetic gene therapies designed to restore vision for people with d...

Berkeley, United States11–50Biotech, Genomics
Series BTotal funding$241.0MApr 2026
98
ELECTRA.AERO INC.

R&D company with 17 SBIR/STTR awards from Department of Defense, Department of Agriculture, Natio...

MANASSAS, United States11–50Defense Tech, Space Tech
Series BTotal funding$239.4MApr 2025
99
MOMA Therapeutics

MOMA Therapeutics develops precision medicines by targeting molecular machines that underlie dise...

Cambridge, United States51–200Biotech, Healthcare
Series BTotal funding$236.0MMay 2022
100
City Therapeutics

Biopharmaceutical company building next-generation RNAi therapeutics to improve treatment for pat...

Cambridge, United States51–200Biotech, Healthcare
Series BTotal funding$234.5MJun 2026