All Rankings

Top Series A Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was Series A, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $35.6B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series A.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

51
Arta

AI-driven digital wealth platform giving accredited investors access to alternative investments a...

San Francisco, United States51–200Artificial Intelligence, Fintech
Series ATotal funding$180.0MNov 2022
52
cAMPfield Therapeutics

Clinical-stage biopharmaceutical company developing prifemilast, an oral PDE4B-selective inhibito...

San Diego, United States1–10Biotech, Healthcare
Series ATotal funding$180.0MJun 2026
53
Muck Rack

Muck Rack helps PR and communications teams discover media, monitor coverage, track sentiment, an...

Miami, United States201–500SaaS
Series ATotal funding$180.0MSep 2022
54
Antares Therapeutics

Antares Therapeutics is a biotechnology company developing first-in-class precision medicines for...

Boston, United States11–50Biotech, Healthcare
Series ATotal funding$177.0MJun 2025
55
Korsana

Biopharmaceutical company developing novel therapies targeting amyloid-beta plaques for Alzheimer...

Waltham, United States11–50Biotech, Healthcare
Series ATotal funding$175.0MFeb 2026
56
Lightspark

Lightspark builds open, instant payment infrastructure that helps banks, wallets, and platforms m...

Los Angeles, United States51–200Crypto & Web3
Series ATotal funding$175.0MMay 2022
57
Santa Ana Bio

Santa Ana Bio develops targeted therapies to stop autoimmune and inflammatory disease at the sour...

Alameda, United States11–50Artificial Intelligence, Healthcare
Series ATotal funding$168.0MJun 2024
58
Fabletics

Subscription-based activewear retailer selling men's and women's athletic apparel, footwear, and ...

El Segundo, United States1001–5000E-Commerce, Fashion
Series ATotal funding$166.8MJun 2025
59
7AI

7AI runs an agentic security platform whose AI agents investigate every security alert end to end...

Boston, United States11–50Artificial Intelligence, Cybersecurity
Series ATotal funding$166.0MDec 2025
60
Syremis

Clinical-stage biopharmaceutical company developing novel medicines for mental health conditions.

Tel Aviv, United States11–50Biotech, Healthcare
Series ATotal funding$165.0MDec 2025
61
The Ambr

The Ambr Group buys Amazon businesses customers love and grows them into household names, formerl...

New York, United States11–50E-Commerce, Retail
Series ATotal funding$162.5MAug 2021
62
Enlaza Therapeutics

Biotech company pioneering covalent biologics — novel protein therapeutics with improved efficacy...

San Diego, United States51–200Biotech
Series ATotal funding$161.0MApr 2024
63
NewLeaf Symbiotics

NewLeaf Symbiotics is a biological technology provider whose specialty is Pink-Pigmented Facultat...

St. Louis, United States11–50Agtech, Biotech
Series ATotal funding$161.0MJun 2026
64
August Bioservices

August Bioservices is a Nashville-based CDMO that provides contract research, development, and ma...

Nashville, United States51–200Biotech
Series ATotal funding$158.6MJun 2026
65
Qualified Health

Healthcare-native enterprise AI platform that helps health systems deploy safe and scalable AI ac...

Palo Alto, United States51–200Artificial Intelligence, Healthcare
Series ATotal funding$158.5MMar 2026
66
Antithesis

Antithesis enables you to ship complex systems faster, with fewer bugs using deterministic simula...

Tysons, United States51–200Developer Tools
Series ATotal funding$152.0MDec 2025
67
Latus Bio

Latus develops precisely delivered gene therapies using proprietary capsids, promoters, and compu...

United States11–50Biotech, Healthcare
Series ATotal funding$151.0MMay 2026
68
DevRev

DevRev builds Computer, an AI-native platform that unifies customer support, product development,...

Palo Alto, United States201–500Artificial Intelligence
Series ATotal funding$150.8MOct 2024
69
Cullinan Oncology

Cullinan Therapeutics develops clinical-stage therapies that modulate the immune system to treat ...

Cambridge, United States51–200Biotech, Healthcare
Series ATotal funding$150.0MOct 2017
70
Eka Robotics

Eka Robotics is building intelligence for the physical world in its native language, force, with ...

Cambridge, United States11–50Artificial Intelligence
Series ATotal funding$150.0MOct 2026
71
Zarminali Pediatrics

Zarminali Pediatrics is a nationwide pediatric multispecialty group providing coordinated primary...

Chicago, United States51–200Life Sciences, Healthcare
Series ATotal funding$150.0MJan 2026
72
Titan

Titan is an award-winning wealth management firm that combines human advisors with technology to ...

New York, United States11–50Financial Services, Fintech
Series ATotal funding$147.0MAug 2025
73
Bitterroot Bio

Bitterroot Bio pioneers cardio-immunology, developing immunotherapies that harness immune cells t...

Palo Alto, United States11–50Biotech
Series ATotal funding$145.0MJun 2023
74
Dyna Robotics

Our mission is to empower businesses by automating repetitive, stationary tasks with affordable, ...

San Francisco, United States11–50Supply Chain
Series ATotal funding$143.5MSep 2025
75
Abdera Therapeutics

Platform biotechnology company developing radiopharmaceuticals for cancer.

San Diego, United States11–50Biotech, Healthcare
Series ATotal funding$142.0MJan 2021