All Rankings

Top Series A Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was Series A, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $35.6B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series A.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

26
ShiftKey

ShiftKey connects independent licensed professionals directly with facilities through a digital m...

Irving, United States1001–5000Healthcare
Series ATotal funding$300.0MJan 2023
27
Emerald AI

Software that aligns AI data center workloads with real-time power grid conditions to manage ener...

Washington, United States1–10Artificial Intelligence, Climate Tech
Series ATotal funding$282.5MAug 2026
28
Sygaldry

YC-backed startup building quantum-accelerated AI servers combining multiple qubit types to speed...

San Francisco, United States1–10Artificial Intelligence, Hardware
Series ATotal funding$278.0MApr 2026
29
Telly, Inc.

Telly offers the first Dual Screen Smart TV.

San Francisco, United States51–200Adtech, Hardware
Series ATotal funding$270.0MAug 2024
30
Axiom Math

Axiom builds a self-improving AI mathematician for formal mathematical reasoning and rigorous ver...

Palo Alto, United States11–50Artificial Intelligence
Series ATotal funding$264.0MMar 2026
31
Fundamental

AI lab building NEXUS, a Large Tabular Model purpose-built for structured enterprise data, enabli...

San Francisco, United States11–50Artificial Intelligence, Data & Analytics
Series ATotal funding$255.0MFeb 2026
32
Mill

Home food recycler that dries and grinds kitchen scraps into odorless grounds repurposed as chick...

San Bruno, United States51–200Climate Tech
Series ATotal funding$250.8MAug 2024
33
Monad

Monad is an Ethereum-compatible Layer-1 blockchain designed for high performance, fast finality, ...

San Francisco Bay Area, United States51–200Crypto & Web3, Compliance
Series ATotal funding$244.0MApr 2024
34
doubleAI

doubleAI is developing AI systems intended to surpass expert-level capabilities in science and te...

New York, United States11–50Artificial Intelligence, Generative AI
Series ATotal funding$241.0MSep 2025
35
Omni Analytics

Omni Analytics is a business intelligence platform helping organizations analyze data with modern...

San Francisco, United States51–200Developer Tools, SaaS
Series ATotal funding$230.5MJul 2026
36
Halcyon

Anti-ransomware cybersecurity platform combining AI-driven endpoint protection, key capture for a...

Austin, United States201–500Cybersecurity
Series ATotal funding$211.0MMar 2026
37
Havoc AI

Havoc AI builds collaborative autonomy software for military and commercial autonomous systems, e...

Providence, United States51–200Artificial Intelligence, Defense Tech
Series ATotal funding$208.2MMay 2026
38
Limit Break

Limit Break creates high-quality free-to-play mobile games designed to keep players engaged and r...

United States51–200Crypto & Web3, Gaming
Series ATotal funding$201.0MAug 2022
39
Airnexis Therapeutics

Clinical-stage biotech developing novel therapeutics for pulmonary diseases, including dual PDE3/...

Palo Alto, United States11–50Biotech, Healthcare
Series ATotal funding$200.0MJan 2026
40
Eridu

AI infrastructure for faster and more efficient data centers

Saratoga, United States51–200Artificial Intelligence, Developer Tools
Series ATotal funding$200.0MMar 2026
41
Tenvie

Tenvie is led by innovators with biotech and precision-medicine expertise, pursuing better lives ...

San Francisco, United States11–50Biotech, Healthcare
Series ATotal funding$200.0MJan 2025
42
Alveus Therapeutics

Alveus Therapeutics is a clinical-stage biopharmaceutical company building a differentiated thera...

Philadelphia, United States11–50Biotech
Series ATotal funding$197.0MMar 2026
43
ClearNote Health

ClearNote Health develops blood-based early cancer detection tests and precision research tools u...

San Diego, United States11–50Healthcare, Biotech
Series ATotal funding$193.8MMay 2026
44
Aera Therapeutics

Biotechnology company developing next-generation genetic medicines using a proprietary protein na...

Boston, United States51–200Biotech, Drug Discovery
Series ATotal funding$193.0MFeb 2023
45
Character.AI

Character.AI empowers people to connect, learn, and tell stories through interactive entertainmen...

Menlo Park, United States201–500Artificial Intelligence, Entertainment
Series ATotal funding$193.0MMar 2023
46
Callio Therapeutics

Callio Therapeutics is a clinical-stage biotech developing dual-payload antibody-drug conjugates,...

Seattle, United States1–10Biotech, Oncology
Series ATotal funding$187.0MMar 2025
47
SimpliSafe

Wireless home security systems designed for easy self-installation and cellular monitoring.

Boston, United States1001–5000E-Commerce
Series ATotal funding$187.0MMay 2014
48
Vega Security

AI-native SecOps platform providing federated security analytics, threat detection, and triage fo...

New York, United States51–200Artificial Intelligence, Cybersecurity
Series ATotal funding$185.0MMar 2026
49
Standard Nuclear

Manufacturer of TRISO nuclear fuel for advanced reactors, supplying utilities and reactor develop...

Oak Ridge, United States11–50Clean Energy, Nuclear Energy
Series ATotal funding$182.0MJan 2026
50
HydraHost

Global marketplace and API for bare-metal GPU servers and clusters, serving AI and HPC platforms ...

Miami, United States11–50Cloud, Infrastructure
Series ATotal funding$180.0MJun 2026