All Rankings

Top Series A Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was Series A, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $35.6B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series A.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

76
Gilgamesh Pharmaceuticals

Gilgamesh Pharmaceuticals develops novel chemical entities for psychiatric disease, using medicin...

New York, United States11–50Healthcare, Mental Health
Series ATotal funding$140.0MMar 2026
77
Serapha Bio

Serapha Bio develops SERP-01, a proprietary in vivo base editing program in a Phase 1/2 clinical ...

San Diego, United States1–10Biotech, Healthcare
Series ATotal funding$138.0MJun 2026
78
Electronic Caregiver

Electronic Caregiver is one of the fastest-growing health and safety monitoring companies in the ...

United States201–500Healthcare, Medical Devices
Series ATotal funding$137.5MJun 2023
79
Jasper

Jasper is a marketing agents platform that helps enterprises orchestrate AI agents to create and ...

Austin, United States51–200Artificial Intelligence, Conversational AI
Series ATotal funding$137.0MOct 2022
80
8090

8090 is an AI-native platform that puts documentation, collaboration, and oversight at the center...

Redwood City, United States51–200Artificial Intelligence
Series ATotal funding$135.0MJun 2026
81
Apiiro

Application security posture management (ASPM) platform that unifies risk visibility, prioritizat...

New York, United States51–200Cybersecurity
Series ATotal funding$135.0MNov 2022
82
Happy Health

Happy Sleep provides FDA-cleared home sleep testing, virtual sleep care, and personalized treatme...

Austin, United States11–50Digital Health, Healthcare
Series ATotal funding$135.0MAug 2026
83
SaveLive

Independent music venue investment and services platform supporting indie venues and promoters; r...

Los Angeles, United States11–50Media, Events
Series ATotal funding$135.0MApr 2022
84
ChipAgents

AI-powered chip design environment that accelerates HDL design, debugging, and verification with ...

Santa Clara, United States51–200Artificial Intelligence, Developer Tools
Series ATotal funding$134.1MAug 2026
85
Zephyr AI

Zephyr AI builds AI-enabled software that turns real-world clinical and biological data into insi...

McLean, United States11–50Artificial Intelligence, Healthcare
Series ATotal funding$129.5MMar 2024
86
CoinList

CoinList is an onchain investing platform that gives users access to token sales, tokenized equit...

San Francisco, United States51–200Crypto & Web3, Fintech
Series ATotal funding$128.2MOct 2021
87
Origin

Employee financial wellness platform offering AI-powered budgeting, investment tools, tax plannin...

San Francisco, United States51–200Financial Services, Fintech
Series ATotal funding$127.5MMar 2026
88
AXONIS THERAPEUTICS, INC.

Axonis Therapeutics is a Boston biotechnology company developing oral KCC2-targeting medicines fo...

Boston, United States11–50Biotech, Neurotechnology
Series ATotal funding$127.5MOct 2024
89
Ambros Therapeutics

Ambros Therapeutics is an Irvine, California clinical-stage biotech developing neridronate, a fir...

Irvine, United States11–50Biotech, Healthcare
Series ATotal funding$125.0MDec 2025
90
Aria Networks

Aria Networks captures telemetry from switches, hosts, and AI workloads to give data-center teams...

Palo Alto, United States11–50Artificial Intelligence, Infrastructure
Series ATotal funding$125.0MApr 2026
91
Coultreon Biopharma

Leuven-based clinical-stage biopharma applying deep SIK pathway expertise and a Design-Predict-Ma...

Leuven, United States11–50Biotech
Series ATotal funding$125.0MApr 2026
92
Kai

Kai is an agentic AI cybersecurity platform that auto-remediates exposures end to end, helping se...

San Jose, United States11–50Artificial Intelligence, Cybersecurity
Series ATotal funding$125.0MMar 2026
93
Nested Therapeutics

Precision oncology biotech identifying novel cancer driver mutations to expand targeted therapy o...

Cambridge, United States11–50Biotech, Healthcare
Series ATotal funding$125.0MOct 2022
94
OnCusp Therapeutics

Clinical-stage biopharma developing targeted oncology therapeutics and ADCs to advance treatments...

Princeton, United States11–50Biotech, Healthcare
Series ATotal funding$125.0MJan 2024
95
Cantina

Social AI platform enabling users to build and interact with realistic AI characters via chat, vo...

Miami, United States11–50Artificial Intelligence
Series ATotal funding$122.8MOct 2025
96
Epignosis

Workplace learning technology vendor offering TalentLMS and eFront platforms serving 70,000+ team...

San Francisco, United States201–500EdTech, SaaS
Series ATotal funding$122.5MJan 2017
97
Slingshot

We place high school prodigies at YC, Techstars companies. Think about what college basketball sc...

Somerset, United States51–200Aerospace, Artificial Intelligence
Series ATotal funding$121.9MAug 2024
98
Merida Biosciences

Merida Biosciences develops precision immunology therapies that target and eliminate the pathogen...

Boston, United States11–50Biotech, Healthcare
Series ATotal funding$121.0MApr 2025
99
Inceptive

Inceptive builds end-to-end foundation models that learn to design molecules from diverse observa...

Palo Alto, United States11–50Artificial Intelligence, Healthcare
Series ATotal funding$120.0MSep 2023
100
RunPod

End-to-end AI cloud platform offering on-demand GPU compute for training and deploying machine le...

San Francisco, United States51–200Artificial Intelligence, Developer Tools
Series ATotal funding$120.0MJun 2026