All Rankings

Top Seed-Stage Companies in the US 2026

Private companies headquartered in the United States whose latest recorded round was seed or pre-seed, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $13.6B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+States&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Seed or Pre-Seed.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

26
Onboard.io

Onboard.io builds customer onboarding software for B2B SaaS post-sale teams, giving implementatio...

Detroit, United States1–10Productivity, SaaS
SeedTotal funding$104.0MMar 2022
27
Paratus Sciences

Biotech company using bat genomics and informatics to discover and develop novel therapeutics for...

New York, United States11–50Biotech, Life Sciences
Pre-seedTotal funding$102.5MJul 2025
28
Ethyreal Bio

Biotech developing ETHY-001, a best-in-class anti-TSHR antibody targeting root causes of Graves' ...

San Francisco, United States1–10Biotech, Healthcare
SeedTotal funding$101.0MJun 2026
29
Aspen Energy Partners

Invests in small- to mid-cap oilfield services and technology companies

Arvada, United States1–10Energy, Oil & Gas
SeedTotal funding$100.0MJan 2016
30
Ent

Enterprise cybersecurity platform.

San Francisco, United States1–10Cybersecurity
SeedTotal funding$100.0MJun 2026
31
Lab1636

Harvard-Deerfield joint translational life science R&D company advancing university innovations t...

New York, United StatesBiotech, Drug Discovery
SeedTotal funding$100.0MMar 2019
32
LMArena

Crowdsourced AI evaluation platform from UC Berkeley researchers where millions of users test and...

San Francisco, United States11–50Artificial Intelligence, Developer Tools
SeedTotal funding$100.0MMay 2025
33
Nvelop Therapeutics

Biotechnology company developing programmable delivery systems for in vivo gene editing and thera...

Cambridge, United States51–200Biotech
SeedTotal funding$100.0MApr 2024
34
Qosmosys

Qosmosys designs space system architectures and lunar infrastructure services for public and priv...

Austin, United States11–50Aerospace
SeedTotal funding$100.0M
35
RadixArk

RadixArk builds open inference and training infrastructure on SGLang and Miles for developers, st...

San Francisco, United States11–50Artificial Intelligence, Infrastructure
SeedTotal funding$100.0MMay 2026
36
Substrate

Building America's next-generation semiconductor foundry using advanced X‑ray lithography to redu...

San Francisco, United States51–200Energy, Hardware
SeedTotal funding$100.0MOct 2025
37
Upwell

Order to Cash Automation for Logistics

San Francisco, United States11–50Supply Chain, Artificial Intelligence
SeedTotal funding$100.0MJul 2020
38
Descope

Developer-focused identity platform providing passwordless authentication, MFA, SSO, and user man...

Los Altos, United States51–200Developer Tools, Identity
SeedTotal funding$88.0MSep 2025
39
Artemis

Artemis is an AI-native protection platform that helps security teams eliminate real cyber threat...

New York, United States1–10Artificial Intelligence, Cybersecurity
SeedTotal funding$85.0MApr 2026
40
Bonus Homes

Home equity platform offering homeowners cash for equity and future appreciation without selling ...

Phoenix, United States1–10PropTech, Fintech
SeedTotal funding$81.0MAug 2025
41
Felux

AI-powered platform that scans a steel service center's email to capture every RFQ, quote, and or...

Cleveland, United States1–10Logistics, Supply Chain
SeedTotal funding$78.3MJun 2026
42
Crux Analytics

Crux equips bankers to strengthen relationships with small businesses and help community financia...

San Francisco, United States1–10Fintech
SeedTotal funding$77.1MSep 2026
43
Healthleap

Healthleap provides AI inpatient risk screening for hospitals, starting with malnutrition: it ana...

San Francisco, United States1–10Artificial Intelligence, Healthcare
SeedTotal funding$77.1MOct 2026
44
Crux Climate

Efficient finance for the energy transition

New York, United States51–200Climate Tech, Fintech
SeedTotal funding$77.0M
45
Ember

AI revenue integrity platform that sits on top of existing EHR and practice management systems, d...

San Francisco, United States1–10Healthcare
SeedTotal funding$75.4MNov 2025
46
0G

Modular blockchain infrastructure for AI agents with decentralized storage, compute, and data ava...

United States51–200Artificial Intelligence, Crypto & Web3
SeedTotal funding$75.0MJan 2025
47
Airship

Mobile-first customer experience platform delivering AI-powered cross-channel experiences includi...

Portland, United States201–500Marketing Tech, SaaS
Pre-seedTotal funding$71.6MSep 2024
48
DEM Bio

DEM Biopharma is a privately held, pre-IND stage biopharmaceutical company based in Cambridge, Ma...

Boston, United States11–50Life Sciences
SeedTotal funding$70.0MJun 2022
49
Edison Scientific

AI platform for scientific discovery enabling researchers to complete literature synthesis, data ...

San Francisco, United States11–50Artificial Intelligence, Deep Tech
SeedTotal funding$70.0MDec 2025
50
Nira Energy

Helps renewable energy developers make smarter siting and queue decisions by modeling grid capaci...

Denver, United States11–50Climate Tech, Energy
SeedTotal funding$65.5MMay 2025