RA Capital Management

Hedge Fund

Boston-based multi-stage investment manager founded in 2004, focused on evidence-based investing in healthcare and life science companies from early-stage formation through commercialization.

Boston, United States · 193+ investments · 154 portfolio companies

Seed
Early Stage
Growth
Late Stage
Public
Biotech
Climate Tech
Healthcare
Life Sciences
Digital Health
Headquarters
Boston, United States
Founded
2004
Website
racap.com
AUM
$12.6B
Portfolio Companies
154
Total Investments
193
Last Investment
Aug 2026
Geographic Focus
North America, United States

Investment Thesis

Evidence-based, multi-stage investing in healthcare and life sciences—drugs, devices, diagnostics, and tools—from early formation through public market commercialization.

RA Capital Management is a Hedge Fund firm based in Boston, United States. It has made 193 investments in Biotech and Climate Tech, including Abcuro, Legend Biotech Corporation and Ventus Tx.

Portfolio154

Abcuro
Legend Biotech Corporation
Ventus Tx
Hemab Therapeutics
Ovid Therapeutics Inc.
Ceribell
Profound Bio
Convergent Therapeutics
Nucleix
Celea Therapeutics
Evommune
Atavistik Bio
Vaxcyte
Vor Biopharma Inc.
Tyra Biosciences
Mineralys Therapeutics
Acumen Pharmaceuticals
Parabilis Medicines
Verona Pharma
Atea Pharmaceuticals
Carmot Therapeutics
Assembly Biosciences
Thriveworks
TRIANA Biomedicines
PepGen
Avalanche Energy
BE Biopharma
Aktis Oncology
Verdiva Bio
Solid Biosciences Inc.
C
Corxel
Ra Pharmaceuticals
Enara Bio
Synthorx
Eidos Therapeutics
Ozlo Sleep
cAMPfield Therapeutics
Trace Neuroscience
Orchard Therapeutics
Dyne Therapeutics
Magenta Medical
Diagonal Therapeutics
FT
Forma Therapeutics
Pluton Biosciences
Tyra
Rivus Pharmaceuticals
Belite Bio
Sidera Bio

Co-investors24

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24 co-investors across 287 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×15 · Other ×3 · Hedge Fund ×3 · 215 shared rounds

Investment History

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