Plexium
Transformative Precision Medicines for Patients in Need
San Diego, United States · Founded 2017 · $197.1M raised
- Headquarters
- San Diego, California
- Employees
- 51–200
- Founded
- 2017
- Business Model
- B2B
- Website
- plexium.com
- Total Funding
- $197.1M
- Last Round
- $60.1M Venture RoundAug 2025
- Rounds
- 4
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
About
Plexium is a next-generation targeted protein degradation (TPD) biotech company developing monovalent degraders — including Monovalent Direct Degraders and Molecular Glues — using a proprietary ultra-high throughput cell-based screening (uHTS) platform. The company's AI-integrated drug discovery approach enables rational design of protein degrader therapeutics for cancer and neurodegenerative diseases. Plexium has established partnerships with Amgen and AbbVie for TPD drug discovery collaborations and maintains a wholly-owned pipeline alongside partnered programs.
Summary
Plexium is a Biotech company based in San Diego, United States, founded in 2017. It has raised $197.1M in total across 4 rounds, most recently a $60.1M Venture Round in Aug 2025. Investors include BVF Partners, TCGX and Lux Capital.
Tech & App Stack
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Funding History
Aug 2025
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Funding: Seed through Venture Round. Amounts, valuations, and investors where available.
Investors
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