Plexium

Transformative Precision Medicines for Patients in Need

San Diego, United States · Founded 2017 · $197.1M raised

Employees
51–200
Founded
2017
Business Model
B2B
Total Funding
$197.1M
Last Round
$60.1M Venture RoundAug 2025
Rounds
4

About

Plexium is a next-generation targeted protein degradation (TPD) biotech company developing monovalent degraders — including Monovalent Direct Degraders and Molecular Glues — using a proprietary ultra-high throughput cell-based screening (uHTS) platform. The company's AI-integrated drug discovery approach enables rational design of protein degrader therapeutics for cancer and neurodegenerative diseases. Plexium has established partnerships with Amgen and AbbVie for TPD drug discovery collaborations and maintains a wholly-owned pipeline alongside partnered programs.

Summary

Plexium is a Biotech company based in San Diego, United States, founded in 2017. It has raised $197.1M in total across 4 rounds, most recently a $60.1M Venture Round round in Aug 2025. Investors include BVF Partners, TCGX and Lux Capital.

Tech & App Stack

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Funding History

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Venture RoundVenture RoundAug 2025
$60.1M

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Investors

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