Lightstone Ventures
Lightstone Ventures is a biotech and medtech venture capital firm founded in 2012, headquartered in Portola Valley, California, with additional offices in Boston and Dublin. The firm invests in first-in-class biotech therapies across CNS, immunology, oncology, and ophthalmology, as well as medtech companies advancing personalized medicine and targeted therapeutics. Its track record includes 20 IPOs and 22 acquisitions among portfolio companies.
Menlo Park, United States · 36+ investments · 63 portfolio companies
- Headquarters
- Menlo Park, United States
- Founded
- 2012
- Website
- lightstonevc.com
- AUM
- $375.0M
- Portfolio Companies
- 63
- Total Investments
- 36
- Last Investment
- Sep 2025
- Geographic Focus
- United States, Ireland, Singapore
Investment Thesis
Lightstone Ventures is a Venture Capital firm based in Menlo Park, United States. It has made 36 investments in Biotech and Medical Devices, including Cabochon Aesthetics, Trishula Therapeutics and Ardian.
Portfolio63
Co-investors24
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24 co-investors across 99 shared portfolio companies — who they back alongside, and how often they lead.
Venture Capital ×19 · Corporate VC ×3 · Private Equity ×1 · 37 shared rounds
Investment History
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