Lightstone Ventures

Venture Capital

Lightstone Ventures is a biotech and medtech venture capital firm founded in 2012, headquartered in Portola Valley, California, with additional offices in Boston and Dublin. The firm invests in first-in-class biotech therapies across CNS, immunology, oncology, and ophthalmology, as well as medtech companies advancing personalized medicine and targeted therapeutics. Its track record includes 20 IPOs and 22 acquisitions among portfolio companies.

Menlo Park, United States · 27+ investments · 55 portfolio companies

Growth
Late Stage
Biotech
Medical Devices
Headquarters
Menlo Park, United States
Founded
2012
AUM
$375.0M
Portfolio Companies
55
Total Investments
27
Last Investment
Aug 2025
Geographic Focus
United States, Ireland, Singapore

Investment Thesis

We invest in personalized medicines and targeted therapeutics.

Lightstone Ventures is a Venture Capital firm based in Menlo Park, United States. It has made 27 investments in Biotech and Medical Devices, including Cabochon Aesthetics, Trishula Therapeutics and Ardian.

Portfolio55

Investment History

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