Vigil Neuroscience
ClosedR&D-Driven and AI-Powered Biopharma Company | Sanofi
Cambridge, United States · Founded 2020 · $140.0M raised
- Headquarters
- Cambridge, Massachusetts
- Employees
- 11–50
- Founded
- 2020
- Business Model
- B2B
- Website
- vigilneuro.com
- Total Funding
- $140.0M
- Last Round
- $90.0M Series BAug 2021
- Rounds
- 2
About
Vigil Neuroscience was a biotechnology company founded in 2020 and headquartered in Cambridge, Massachusetts, focused on harnessing the power of microglia to develop treatments for neurodegenerative diseases. The company pipeline centered on TREM2 (Triggering Receptor Expressed on Myeloid cells 2), a key receptor that regulates microglial function in the brain, with both antibody and small molecule agonist programs targeting neuroinflammation in Alzheimer disease, rare leukodystrophies, and other CNS conditions. Vigil lead programs included VGL101, an anti-TREM2 antibody for CSF1R-related leukodystrophy, and VG-3927, a novel oral small molecule TREM2 agonist. The company raised $140 million in financing before being acquired by Sanofi in 2025 for $470 million, adding its investigational TREM2 agonist to Sanofi neurology pipeline.
Summary
Vigil Neuroscience is a Biotech company based in Cambridge, United States, founded in 2020. It has raised $140.0M in total across 2 rounds, most recently a $90.0M Series B round in Aug 2021. Investors include Atlas Venture, Sanofi Ventures and Vida Ventures.
Tech & App Stack
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Funding History
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Aug 2025
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Series A through Acquisition — per-round amounts, valuations, and who invested in each round.
Investors
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