Crystalys Therapeutics
Transforming care for people living with gout.
San Diego, United States · Founded 2025 · $335.0M raised
- Headquarters
- San Diego, California
- Employees
- 11–50
- Founded
- 2025
- Business Model
- B2B
- Website
- crystalystx.com
- Total Funding
- $335.0M
- Last Round
- $130.0M Series BJul 2026
- Rounds
- 2
About
Crystalys Therapeutics is a clinical-stage biopharmaceutical company headquartered in San Diego, California, focused on transforming the treatment of gout — a disease that affects an estimated 10 million Americans yet remains poorly served by existing therapies. The company's lead candidate, dotinurad, is a next-generation URAT1 inhibitor that addresses difficult-to-treat and refractory gout cases that cannot be adequately managed with generic allopurinol. Crystalys launched in September 2025 with a $205 million Series A financing round and is currently conducting Phase 2 clinical trials, with first patients dosed in May 2026. The company was founded by an experienced team with deep background in uric acid biology and URAT1 inhibitor mechanisms.
Summary
Crystalys Therapeutics is a Biotech company based in San Diego, United States, founded in 2025. It has raised $335.0M in total across 2 rounds, most recently a $130.0M Series B round in Jul 2026. Investors include Novo Holdings A/S, SR One and Catalys Pacific.
Tech & App Stack
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Funding History
Jul 2026
Sign up to see all 2 rounds
Series A through Series B — per-round amounts, valuations, and who invested in each round.
Investors
Novo Holdings A/S
2 rounds
SR One
2 rounds
Catalys Pacific
2 rounds
Frazier Life Sciences
1 round
Wellington Management
2 rounds
HBM Healthcare Investments
1 round
Soleus Capital
1 round
Cormorant
1 round
HBM Partners
1 round
Cormorant Asset Management
1 round
Frazier Healthcare
1 round
Lightstone Ventures
1 round
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