All Rankings

Top 100 AI Startups in Seattle 2026

The most-funded artificial intelligence and machine learning startups headquartered in Seattle, ranked by total capital raised.

Known total funding for 100 of 100 ranked companies: $3.9B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?industries=Artificial+Intelligence,Generative+AI,Machine+Learning&countries=United+States&cities=Seattle&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant, private equity or debt financing; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant, Private Equity, Debt Financing are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

1
Truveta

Truveta provides de-identified, real-world healthcare data and analytics that help life sciences ...

Seattle, United States201–500Artificial Intelligence, Data & Analytics
Series CTotal funding$415.0MJan 2025
2
XBOW

XBOW is an AI-powered offensive security company that automates pentesting and accelerates the di...

Seattle, United States51–200Artificial Intelligence, Cybersecurity
Extension RoundTotal funding$270.0MMay 2026
3
Karat

Karat is a workforce transformation partner that combines live interviews from trained Interview ...

Seattle, United States201–500Artificial Intelligence, SaaS
Series CTotal funding$199.7MOct 2021
4
Stackline

Stackline provides consumer brands with ecommerce intelligence and automation software for analyz...

Seattle, United States201–500Analytics, E-Commerce
Venture RoundTotal funding$180.0MJun 2021
5
Outpace Bio

Seattle biotech using AI-powered protein design to engineer next-generation cell therapies, impro...

Seattle, United States51–200Artificial Intelligence, Biotech
Series BTotal funding$174.0MAug 2024
6
Seeq

Seeq provides advanced industrial analytics and AI software that helps process manufacturers unlo...

Seattle, United States201–500Artificial Intelligence, Data & Analytics
Series DTotal funding$153.0MAug 2024
7
Shape Therapeutics

A development stage biotechnology company based in Seattle WA and San Diego CA that is establishi...

Seattle, United States51–200Artificial Intelligence, Biotech
Series BTotal funding$147.5M
8
Overland AI

Builds autonomous off‑road ground vehicles and an autonomy stack for defense customers, providing...

Seattle, United States51–200Artificial Intelligence, Autonomous Vehicles
Series BTotal funding$143.5MFeb 2026
9
Gradial

AI-powered content operations platform that automates enterprise marketing workflows using agenti...

Seattle, United States11–50Artificial Intelligence, Marketing Tech
Series CTotal funding$118.4MJun 2026
10
Amperity

Intelligent Customer Data Platform using AI-powered identity resolution to help global consumer b...

Seattle, United States201–500Artificial Intelligence, Data & Analytics
Series DTotal funding$100.0MJul 2021
11
Phaidra

Builds AI agents that optimize power, cooling, and workload management for AI data centers to max...

Seattle, United States51–200Artificial Intelligence, Industrials
Series BTotal funding$87.0MOct 2025
12
Supio

Legal AI platform that automates medical record review and drafting for personal injury law firms...

Seattle, United States51–200Artificial Intelligence, Legal Tech
Series BTotal funding$85.0MApr 2025
13
Edge Delta

Provides AI-driven observability and telemetry pipelines for SRE, DevOps, and security teams to d...

Seattle, United States51–200Artificial Intelligence, Data & Analytics
Series BTotal funding$81.0MMay 2022
14
Read AI

AI copilot that transforms meetings, emails, and messages into summaries and insights for enterpr...

Seattle, United States51–200Artificial Intelligence, SaaS
Series BTotal funding$81.0MOct 2024
15
Vilya

Vilya designs novel macrocycle therapeutics using AI-driven computation, combining the targeting ...

Seattle, United States11–50Artificial Intelligence, Biotech
Series ATotal funding$71.0MJun 2024
16
Defined.ai

Defined.ai is a global marketplace for ethical AI training data, enabling enterprises to build re...

Seattle, United StatesArtificial Intelligence
Extension RoundTotal funding$66.6MJan 2022
17
Proprio

AI-powered surgical intelligence platform combining physician expertise with immersive technology...

Seattle, United States51–200Artificial Intelligence, Healthcare
Series BTotal funding$66.0MJul 2023
18
iUNU

Agricultural technology platform delivering plant-level greenhouse insights that help growers imp...

Seattle, United States51–200Artificial Intelligence, Climate Tech
Growth EquityTotal funding$64.5MApr 2025
19
Augmodo

Augmodo provides Spatial AI that tracks every product in every store in real time, with a real-ti...

Seattle, United States11–50Artificial Intelligence
Series ATotal funding$63.8MJul 2025
20
Yoodli

Enterprise AI roleplay platform for communication coaching, sales enablement, and L&D training. T...

Seattle, United States11–50Artificial Intelligence, SaaS
Series BTotal funding$60.4MDec 2025
21
Nuance Labs

Builds real-time, multimodal foundation models that understand and express human emotion across s...

Seattle, United States1–10Artificial Intelligence, Computer Vision
Series ATotal funding$60.0MSep 2026
22
Dropzone AI

Dropzone AI builds AI agents that investigate alerts, hunt threats, and respond to attacks alongs...

Seattle, United States11–50Artificial Intelligence, Cybersecurity
Series BTotal funding$57.3MJul 2025
23
QA Wolf

End-to-end automated QA and test maintenance for engineering teams, delivering high test coverage...

Seattle, United States51–200Artificial Intelligence, Developer Tools
Series BTotal funding$56.0MJul 2024
24
Union.ai

Union AI provides a unified orchestration platform for Machine Learning workflows, data pipelines...

Seattle, United States11–50Artificial Intelligence, Developer Tools
Extension RoundTotal funding$48.1MFeb 2026
25
A-Alpha Bio

A-Alpha Bio harnesses synthetic biology and machine learning to measure, predict, and engineer pr...

Seattle, United States11–50Artificial Intelligence, Biotech
Series ATotal funding$46.9MJul 2023