All Rankings

Top 100 AI Startups in Boston 2026

The most-funded artificial intelligence and machine learning startups headquartered in Boston and Cambridge, Massachusetts, ranked by total capital raised.

Known total funding for 100 of 100 ranked companies: $14.3B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?industries=Artificial+Intelligence,Generative+AI,Machine+Learning&countries=United+States&cities=Boston,Cambridge&states=Massachusetts&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API state filter leaves out companies with no recorded state; this list keeps them when the city matches.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant, private equity or debt financing; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant, Private Equity, Debt Financing are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

26
Ataccama

Enterprise data trust platform providing AI-powered data quality, governance, observability, and ...

Boston, United States501–1000Artificial Intelligence, Data & Analytics
Growth EquityTotal funding$150.0MJun 2022
27
Eka Robotics

Eka Robotics is building intelligence for the physical world in its native language, force, with ...

Cambridge, United States11–50Artificial Intelligence
Series ATotal funding$150.0MOct 2026
28
Lumafield

Industrial CT scanning and AI-powered inspection platform enabling engineers to see inside their ...

Cambridge, United States51–200Artificial Intelligence, Hardware
Series CTotal funding$142.5MMar 2025
29
nference

Agentic AI platform activating real-world clinical EMR data to personalize care pathways and acce...

Cambridge, United States201–500Artificial Intelligence, Biotech
Series CTotal funding$131.0MDec 2020
30
Insurify

AI-powered insurance comparison platform that lets consumers shop, buy, and manage auto and home ...

Cambridge, United States201–500Artificial Intelligence, Fintech
Series BTotal funding$123.0MSep 2021
31
POSH

Conversational AI platform for financial institutions, automating banking contact centers via voi...

Boston, United States51–200Artificial Intelligence, Financial Services
Series BTotal funding$117.5MMar 2026
32
HyperLight

HyperLight is the provider of high-performance TFLN photonic integrated circuits, powering AI, da...

Cambridge, United States11–50Artificial Intelligence
Series CTotal funding$117.0MJun 2026
33
CodaMetrix

AI-powered platform that automates medical coding for health systems, improving coding accuracy, ...

Boston, United States51–200Artificial Intelligence, Healthcare
Series BTotal funding$107.0MMar 2024
34
JuliaHub

Cloud platform for scientific and technical computing, offering AI-native modeling, simulation, a...

Cambridge, United States51–200Artificial Intelligence, Cloud
Series BTotal funding$106.6MApr 2026
35
METiS Pharmaceuticals

METiS is an AI-driven biotechnology company using targeted drug-delivery technology to develop mo...

Cambridge, United States51–200Artificial Intelligence, Biotech
Series DTotal funding$100.0MAug 2025
36
CloudZero

CloudZero provides cloud and AI cost intelligence and optimization for engineering and finance te...

Boston, United States51–200Analytics, Artificial Intelligence
Series CTotal funding$93.0MMay 2025
37
RightHand Robotics

RightHand Robotics builds AI-driven RightPick robots that autonomously piece-pick hundreds of tho...

Cambridge, United States51–200Artificial Intelligence, Logistics
Series CTotal funding$89.8MFeb 2022
38
Botkeeper

See how 250+ Botkeeper firms are saving time & increasing profit with the only badass bookkeeping...

Boston, United States201–500Artificial Intelligence, Fintech
Series CTotal funding$89.5MNov 2021
39
Manifold Bio

Manifold Bio builds a high-throughput in vivo discovery engine that combines multiplexed screenin...

Cambridge, United States1–10Biotech, Drug Discovery
Extension RoundTotal funding$89.4MJan 2024
40
Maven AGI

Builds enterprise AI agents that automate customer support and operations, unifying knowledge and...

Boston, United States51–200Artificial Intelligence, Conversational AI
Series BTotal funding$86.0MJun 2025
41
mabl

AI-native test automation platform for web, mobile, and APIs enabling software teams to accelerat...

Boston, United States51–200Artificial Intelligence, Developer Tools
Series CTotal funding$80.0MNov 2021
42
Tamr

Next-generation platform for extracting, transforming, and loading ("ETL")/processing data

Cambridge, United States201–500Data & Analytics, Machine Learning
Growth EquityTotal funding$78.2MOct 2026
43
Fairmarkit

Fairmarkit is the leading Autonomous Sourcing platform that closes the gap between what procureme...

Boston, United States51–200Artificial Intelligence, SaaS
Series CTotal funding$77.5MSep 2022
44
Zus Health

Zus Health is a shared health data platform that gives care teams a single, shareable view of a p...

Boston, United States51–200Artificial Intelligence, Healthcare
Series BTotal funding$74.0MMar 2023
45
Sea Machines Robotics

Sea Machines develops retrofit autonomy and navigation systems for commercial and defense vessels...

Boston, United States11–50Artificial Intelligence, Autonomous Vehicles
Series CTotal funding$73.5MMar 2025
46
Wise Systems

Wise Systems provides machine learning-powered dispatch and routing software that optimizes last-...

Cambridge, United States51–200Artificial Intelligence, Data & Analytics
Series CTotal funding$72.0MOct 2021
47
Flipside Crypto

Provides on-chain analytics, SQL-ready blockchain data, and AI agents to crypto projects and ente...

Boston, United States51–200Artificial Intelligence, Business Intelligence
Series ATotal funding$68.6MOct 2025
48
Smartcat

AI translation and localization platform helping enterprises create, translate, and manage global...

Boston, United States201–500Artificial Intelligence, Developer Tools
Series CTotal funding$67.8MSep 2024
49
VideaHealth

VideaHealth (now VideaAI) uses artificial intelligence to detect dental conditions on X-rays, ser...

Boston, United States51–200Artificial Intelligence, Healthcare
Series BTotal funding$66.5MJan 2025
50
PhaseV

PhaseV is a Boston-based company that uses causal machine learning and generative AI to help biop...

Cambridge, United States11–50Artificial Intelligence, Healthcare
Series ATotal funding$65.0MMay 2025