Who is the most active healthcare investor?

Y Combinator is the most active investor in funding rounds into healthcare companies tracked by Indexed, with 585 documented rounds (311 as lead) across 496 companies, as of September 2026.

Which firms are the most active healthcare investors right now?

The most active investors in funding rounds into healthcare companies are Y Combinator, National Institutes of Health, Techstars, General Catalyst, New Enterprise Associates — ranked by documented round participation as of September 2026.

How is "most active" measured?

Investors are ranked by the number of distinct documented funding rounds into healthcare companies they participated in — every round sourced from a verifiable public record and confidence-checked. "Led" counts rounds where the investor was a lead. Ranking is by deal count, not capital deployed.

Data Report

Most Active Healthcare Investors 2026

Name: Most Active Healthcare Investors 2026
Creator: Indexed
License: https://indexed.vc/terms

Investors ranked by documented funding rounds into healthcare, biotech, digital health and medical-device companies. A cut of the full venture league table.

Data as of September 2026 · Updated continuously · Figures in USD

Ranked Here

585

Top Firm Rounds

311

Top Firm Led

22,293+

Investors Tracked

The League Table

Ranked by documented funding rounds into healthcare companies participated in and led.

InvestorRoundsLedCompanies

Y Combinator

VC · United States

585311496 2

National Institutes of Health

Government · United States

328299233 3

Techstars

Accelerator · United States

319202304 4

General Catalyst

VC · United States

312180208 5

New Enterprise Associates

VC · United States

284139189 6

OrbiMed

VC · United States

276130204 7

Corporate VC · United States

24492167 8

SOSV

Accelerator · United States

232124192 9

Andreessen Horowitz

VC · United States

220124144 10

Khosla Ventures

VC · United States

217114134 11

Polaris Partners

VC · United States

21594138 12

F-Prime Capital

VC · United States

21469152 13

ARCH Venture Partners

VC · United States

213108136 14

RA Capital Management

Hedge Fund · United States

17980145 15

Sofinnova Partners

VC · France

17196112 16

Sequoia Capital

VC · United States

16265112 17

Alumni Ventures

VC · United States

15622140 18

Novo Holdings A/S

VC · Denmark

14174113 19

European Innovation Council Fund

Government · Belgium

13378102 20

Plug and Play

Accelerator · United States

12737117 21

Kleiner Perkins

VC · United States

1135569 22

8VC

VC · United States

1133680 23

Lux Capital

VC · United States

1094875 24

Founders Fund

VC · United States

1083563 25

500 Global

VC · United States

1074298 26

Bessemer Venture Partners

VC · United States

1065067 27

Antler

Accelerator · United States

10571100 28

Deerfield Management

VC · United States

1056785 29

Atlas Venture

VC · United States

1055072 30

Venrock

VC · United States

1035473 31

Eight Roads Ventures

VC · United Kingdom

1035176 32

Alexandria Venture Investments

VC · United States

103986 33

Lightspeed Venture Partners

VC · United States

1006073 34

Insight Partners

VC · United States

997068 35

Qiming VP

VC · United States

935167 36

DCVC (Data Collab)

VC · United States

924863 37

Pfizer Ventures

Corporate VC · United States

923577 38

Norwest Venture Partners

VC · United States

915966 39

Temasek

Sovereign · Singapore

914867 40

Accel

VC · United States

904455 41

Fidelity Management

Investor · United States

873271 42

Flare Capital Partners

VC · United States

864759 43

Viking Global

Hedge Fund · United States

843062 44

Canaan Partners

VC · United States

833962 45

Morningside Group

VC · Hong Kong

824964 46

Bpifrance

Investor · France

812662 47

SoftBank

VC · United Kingdom

805368 48

IndieBio

Accelerator · United States

803972 49

Johnson & Johnson Innovation

VC · United States

772763 50

Versant Ventures

VC · United States

764054

Explore More

All Most Active Investors Most Active Pre-Seed Investors Most Active Seed Investors Most Active Series A Investors Most Active Series B Investors Most Active Growth-Stage Investors All Reports

Methodology

Figures are aggregated from Indexed's live database of 100,049+ private companies and 22,293+ investors. Every funding round is sourced from a verifiable public record; duplicates are merged and only rounds meeting a confidence threshold are counted. Amounts are whole USD; undisclosed rounds are excluded from dollar totals but counted where noted. "Documented" means announced with a citable source — true market totals are higher. Data as of September 2026 and updated continuously. Free to cite with attribution to Indexed.