Hercules Capital
Venture Capital
Largest non-bank venture debt provider to high-growth tech and life sciences companies.
San Mateo, United States · 38+ investments · 493 portfolio companies
Growth
Life Sciences
- Headquarters
- San Mateo, United States
- Founded
- 2003
- Website
- htgc.com
- AUM
- $5.0B
- Portfolio Companies
- 493
- Total Investments
- 38
- Last Investment
- May 2026
- Geographic Focus
- United States
Investment Thesis
Leading provider of venture debt to innovative technology and life sciences companies, offering flexible capital solutions to venture-backed innovators without equity dilution.
Hercules Capital is a Venture Capital firm based in San Mateo, United States. It has made 38 investments in Life Sciences, including Althea Technologies, PerfectServe and SingleStore.
Portfolio493
AT
Althea Technologies
PS
PSS Systems
A
Atrenta
P
PathfireBS
Baxano SurgicalOB
Optiscan BiomedicalC
CaleraBT
Better TherapeuticsO
OATSystemsMP
Memory Pharmaceuticals
AS
Agami SystemsCP
Celator Pharmaceuticals
D
Diomed
O
Optovia
CC
CytRx CorporationCP
Concert Pharmaceuticals
JA
Jaguar Animal Health
A
AHHHA
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Co-investors24
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24 co-investors across 263 shared portfolio companies — who they back alongside, and how often they lead.
Venture Capital ×17 · Hedge Fund ×3 · Corporate VC ×2 · 6 shared rounds
Investment History
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