Sift Biosciences

Harnessing hidden immunity to fight cancer and autoimmunity.

Seattle, United States · Founded 2024 · $3.7M raised

Employees
1–10
Founded
2024
Business Model
B2B
Total Funding
$3.7M
Last Round
$3.7M Pre-SeedFeb 2026
Rounds
1

About

Sift Biosciences is a San Carlos, California-based peptide immunotherapy company spun out of UC Berkeley. The company has built a proprietary platform combining AI-driven discovery, metagenomics, and high-throughput T-cell screening to identify microbially derived peptides that activate pre-existing memory T cells capable of targeting cancer and autoimmune diseases. By borrowing signals from bacteria and viruses that frequently interact with the human immune system, Sift aims to develop a new class of targeted, durable immunotherapies for cancers and autoimmune conditions where current therapies fall short. The company raised $3.7M in an oversubscribed pre-seed round in early 2026 and was co-founded by Yue Clare Lou, Ph.D. (Forbes 30 Under 30) and Maddie Williams.

Summary

Sift Biosciences is a Healthcare company based in Seattle, United States, founded in 2024. It has raised $3.7M in total across 1 round, most recently a $3.7M Pre-Seed round in Feb 2026. Investors include Freeflow Ventures, Lifespan Vision Ventures and SBI US Gateway Fund.

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