All Rankings

Top Series B Companies in the UK 2026

Private companies headquartered in the United Kingdom whose latest recorded round was Series B, ranked by disclosed lifetime funding.

Known total funding for 100 of 100 ranked companies: $14.2B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?countries=United+Kingdom&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no funding stage filter, so this includes every stage, not only Series B.

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

1
Isomorphic Labs

AI-first drug discovery company using AlphaFold-derived models to design therapeutics and acceler...

London, United Kingdom201–500Artificial Intelligence, Biotech
Series BTotal funding$2.6BMay 2026
2
CuspAI

CuspAI is a frontier AI company pioneering the discovery of breakthrough materials to power human...

Cambridge, United Kingdom11–50Artificial Intelligence, Climate Tech
Series BTotal funding$1.2BJul 2026
3
O
Olix

UK AI-chip startup building optical compute chips to rival GPU incumbents.

London, United KingdomArtificial Intelligence, Semiconductors
Series BTotal funding$532.0MAug 2026
4
Fractile

Fractile builds processors that physically interleave memory and compute to deliver low-latency, ...

London, United Kingdom51–200Artificial Intelligence, Semiconductors
Series BTotal funding$464.2MMay 2026
5
Signal AI

Signal AI is a risk and reputation intelligence company that uses proprietary AI to analyze 2 bil...

London, United Kingdom201–500Artificial Intelligence, SaaS
Series BTotal funding$348.8MFeb 2026
6
Zapp

Zapp is a London premium convenience delivery app that brings hand-picked groceries, pharmacy ite...

London, United Kingdom201–500E-Commerce, Transportation
Series BTotal funding$300.0MJan 2022
7
Stability AI

Open-source generative AI company building multimodal image, audio, video, and 3D models for ente...

London, United Kingdom51–200Artificial Intelligence
Series BTotal funding$257.0MAug 2026
8
Quell Therapeutics

Clinical stage company transforming lives in immune mediated disease

London, United Kingdom51–200Biotech, Healthcare
Series BTotal funding$240.0MNov 2021
9
T Therapeutics

T-Therapeutics develops first-in-class TCR-based medicines for cancer and autoimmune disease usin...

Cambridge, United Kingdom11–50Biotech, Healthcare
Series BTotal funding$225.0MNov 2026
10
Draig Therapeutics

Draig develops highly specific AMPA and GABAA receptor modulators to precisely address neuropsych...

Cardiff, United Kingdom1–10Biotech
Series BTotal funding$205.0MJul 2026
11
Tripledot

Tripledot Studios is a London-based mobile game studio known for casual games like Woodoku, Solit...

London, United Kingdom501–1000Gaming
Series BTotal funding$202.0MFeb 2022
12
Pheon Therapeutics

Pheon Therapeutics develops antibody-drug conjugates based on novel targets and linker payloads t...

Harpenden, United Kingdom11–50Biotech, Healthcare
Series BTotal funding$188.0MMay 2024
13
GWI

GWI provides human insights for brands and agencies, helping them understand audiences and make d...

London, United Kingdom501–1000Adtech, Analytics
Series BTotal funding$180.0MFeb 2022
14
Kraken Technology Group

British maritime defence technology company.

Fareham, United Kingdom51–200Defense Tech
Series BTotal funding$175.0MJul 2026
15
McGill and Partners

London-based specialist insurance and reinsurance broker with 600+ colleagues globally, serving l...

London, United Kingdom501–1000Fintech
Series BTotal funding$175.0MJun 2026
16
AviadoBio

AviadoBio is a biotechnology company developing transformative gene therapies for neurodegenerati...

London, United Kingdom51–200Biotech, Genomics
Series BTotal funding$168.5MApr 2025
17
Purespring

AAV-based gene therapies for kidney diseases

London, United Kingdom11–50Biotech, Healthcare
Series BTotal funding$165.0MOct 2024
18
Xelix

Since 2018, Xelix has been a pioneer in the Accounts Payable audit and controls space.

London, United Kingdom51–200Financial Services
Series BTotal funding$165.0MJul 2025
19
BVNK

Provides enterprise-grade stablecoin payments infrastructure enabling businesses to send, receive...

London, United Kingdom201–500Crypto & Web3, Fintech
Series BTotal funding$140.0MJun 2026
20
Ori Biotech

Ori Biotech builds the IRO platform that automates cell and gene therapy manufacturing and helps ...

London, United Kingdom11–50Biotech
Series BTotal funding$139.4MJan 2022
21
Dwelly

Acquires independent UK lettings agencies and provides an AI-powered property-management platform...

London, United Kingdom11–50PropTech, Real Estate
Series BTotal funding$138.2MJul 2026
22
Envelop Risk

Underwriting firm specialising in cyber reinsurance, providing underwriting, structuring, and cap...

Bristol, United Kingdom11–50Cybersecurity, Insurance
Series BTotal funding$136.0MJan 2021
23
Ramp Network

Ramp Network builds on-ramp and off-ramp solutions that connect the crypto economy with financial...

London, United Kingdom51–200Crypto & Web3, Fintech
Series BTotal funding$134.0MNov 2022
24
CHARM Therapeutics

AI-driven biotech developing next-generation menin inhibitors and small-molecule therapeutics for...

London, United Kingdom11–50Life Sciences, Biotech
Series BTotal funding$130.0MSep 2025
25
Plum

Plum is a money app that automatically helps people save and invest through automations, easy-acc...

London, United Kingdom11–50Artificial Intelligence, Fintech
Series BTotal funding$128.7MMar 2026