CHARM Therapeutics
Protein-ligand intelligence to deliver next-generation small molecule therapeutics
London, United Kingdom · Founded 2021 · $130.0M raised
- Headquarters
- London
- Employees
- 11–50
- Founded
- 2021
- Business Model
- B2B
- Website
- charmtx.com
- Total Funding
- $130.0M
- Last Round
- $80.0M Series BSep 2025
- Rounds
- 2
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
About
Charm Therapeutics is an AI-driven drug discovery company using deep learning to design highly potent small molecule medicines. Founded by leaders with a track record in AI and drug discovery, the company applies its proprietary protein-ligand interaction platform to engineer structurally optimized inhibitors. Charm's lead program focuses on next-generation menin inhibitors for Acute Myeloid Leukemia (AML) — designed to overcome treatment resistance observed in first-generation therapies by reprogramming leukemic cells rather than simply killing them. Headquartered in London with a research presence at the Babraham Research Campus in Cambridge, Charm is advancing its pipeline toward clinical-stage validation.
Summary
CHARM Therapeutics is a Life Sciences company based in London, United Kingdom, founded in 2021. It has raised $130.0M in total across 2 rounds, most recently a $80.0M Series B round in Sep 2025.
Tech & App Stack
3 technologies & apps tracked
Every product and vendor across these categories, with where each signal came from.
Create a free account with 25 free credits every month, no card needed, to unlock the full tech & app stack, funding history, and valuations.
Funding History
Sep 2025
Sign up to see all 2 events
Funding: Series A through Series B. Amounts, valuations, and investors where available.
Similar Companies
San Diego-based clinical stage biopharmaceutical company focused on the development of small mole...
Chai Discovery builds frontier AI to predict and reprogram interactions between biochemical molec...
AI-first drug discovery company using AlphaFold-derived models to design therapeutics and acceler...
Asymchem is a pharmaceutical CDMO providing R&D, chemistry, manufacturing, and control services t...
Appears in
Your company? Embed this profile
Add the live badge to your site — it stays current as your funding data updates.
<a href="https://indexed.vc/companies/charm-therapeutics"><img src="https://indexed.vc/api/badge/company/charm-therapeutics" alt="CHARM Therapeutics on Indexed.vc" width="260" height="76" /></a>