Unnatural Products
Pioneering the development of synthetic macrocyclic peptides
Santa Cruz, United States · Founded 2016 · $83.0M raised
- Headquarters
- Santa Cruz, California
- Employees
- 11–50
- Founded
- 2016
- Business Model
- B2B
- Website
- unnaturalproducts.com
- Total Funding
- $83.0M
- Last Round
- $45.0M Series BMar 2026
- Rounds
- 3
About
Unnatural Products pioneers synthetic macrocyclic peptides that combine antibody-like precision with small-molecule oral delivery for intra- and extracellular targets. Born out of the Lokey Lab, the company built a scalable platform that unites digital and physical lab technologies in a continuous optimization loop to improve potency, selectivity, and permeability. Its internal portfolio focuses on high-value biology inaccessible to traditional small molecules, and it partners with industry leaders including Novartis, Merck, Argenx, and BridgeBio on undruggable targets.
Summary
Unnatural Products is a Biotech company based in Santa Cruz, United States, founded in 2016. It has raised $83.0M in total across 3 rounds, most recently a $45.0M Series B round in Mar 2026. Investors include Artis Ventures (AV), The Venture Collective and Merck Global Health Innovation Fund.
Tech & App Stack
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Funding History
Mar 2026
Sign up to see all 3 rounds
Seed through Series B — per-round amounts, valuations, and who invested in each round.
Investors
Artis Ventures (AV)
3 rounds
The Venture Collective
2 rounds
Merck Global Health Innovation Fund
2 rounds
First Spark Ventures
2 rounds
Droia Ventures
1 round
HUMAIN
1 round
LongeVC
1 round
Not Boring Capital
1 round
Abstract Ventures
1 round
Asset Management Ventures
1 round
better ventures
1 round
Blue Bear Capital
1 round
Rising Tide
1 round
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