SyntheX

SyntheX is a San Francisco-based biotechnology company advancing precision drug discovery through synthetic biology. Its proprietary ToRFLEx platform uses genetically engineered cells for target-centric functional selection, enabling drug discovery against challenging protein targets and complex mechanisms of action — including protein-protein interaction inhibitors and proximity inducers for targeted protein degradation. SyntheX maintains a differentiated internal oncology pipeline targeting genetically validated, previously inaccessible proteins, alongside external collaboration programs to broaden the platform's reach.