Cofactor Genomics

Cofactor closes the precision medicine gap with predictive diagnostics

St. Louis, United States · Founded 2015 · $19.4M raised

Employees
11–50
Founded
2015
Business Model
B2B
Total Funding
$19.4M
Last Round
Series BDec 2025
Rounds
3

Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.

Indexed holds 3 funding rounds and 7 investors for this company. The full record is or through the API.

About

Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data. The team recently had their technology validation peer-reviewed by the organizations that set standards for diagnostic technology (CAP, AMP) and is publishing in the Journal of Molecular Diagnostics. In addition, the team made news when Cancer Physicians who sit on the committee for patient treatment guidelines (NCCN) presented a clinical study using Cofactor’s technology showing superiority in predicting the patients who will respond to immunotherapy. This initial application is an acute problem recognized widely in the rapidly developing immunotherapy industry and represents north of a billion dollar TAM. After a number of recent key milestones, the team is taking the technology more broadly to 50% of cancers diagnosed in the US. Current investors include Menlo Ventures, DCVC, and Ascension Ventures (this last investor representing the funding arm for 13 National U.S. Healthcare Systems).

Summary

Cofactor Genomics is a Biotech company based in St. Louis, United States, founded in 2015. It has raised $19.4M in total across 3 rounds, most recently a Series B round in Dec 2025. Investors include Ascension Ventures, Labcorp and Menlo Ventures.

Tech & App Stack

11 technologies & apps tracked

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Funding History

Series BSeries BDec 2025

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Funding: Grant through Series B. Amounts, valuations, and investors where available.

Investors

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