Alpheus Medical
formerly AlpheusAlpheus Medical is a biotech company in Chanhassen, United States, founded in 2014. It has raised $84.0M across 4 rounds, most recently a $52.0M Series B in May 2025.
Developing a New Drug-Ultrasound Therapy for Glioblastoma
- Headquarters
- Chanhassen, Minnesota
- Employees
- 11–50
- Founded
- 2014
- Business Model
- B2B
- Website
- alpheusmedical.com
- Total Funding
- $84.0M
- Last Round
- $52.0M Series BMay 2025
- Rounds
- 4
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
Indexed holds 4 funding rounds and 7 investors for this company. The full record is or through the API.
About
Alpheus Medical is a private, clinical-stage biotechnology company headquartered in Chanhassen, Minnesota, developing Porphyrin Metabolite Activation (PoMA), a drug-led, tumor-selective oncology approach for the treatment of glioblastoma. The company's therapy is designed to activate 5-ALA-derived protoporphyrin IX (PpIX) localized within tumor tissue using proprietary low-intensity defocused ultrasound, enabling targeted pharmacologic activity without systemic side effects. Founded by Dr. Vijay Agarwal, Alpheus's lead program is currently being evaluated in a randomized Phase 2b clinical trial for newly diagnosed glioblastoma patients who continue standard-of-care treatment alongside the investigational therapy. In May 2025, Alpheus closed a $52 million Series B funding round to support the expanded clinical trial. The company's scientific advisory board includes leading neuro-oncologists from Northwestern University, Harvard Medical School, and Dana-Farber Cancer Institute.
Summary
It lists 11–50 employees. It has raised $84.0M in total across 4 rounds, most recently a $52.0M Series B round in May 2025. Investors include OrbiMed, Action Potential Venture Capital and HealthQuest Capital.
Tech & App Stack
4 technologies & apps tracked
Every product and vendor across these categories, with where each signal came from.
Create a free account with 25 free credits every month, no card needed, to unlock the full tech & app stack, funding history, and valuations.
Funding History
May 2025
Sign up to see all 4 events
Funding: Series A through Series B. Amounts, valuations, and investors where available.
Investors
Similar Companies
BeOne Medicines develops transformative oncology medicines through rigorous science, an accelerat...
China's leading blood products manufacturer
Global contract research organization providing comprehensive drug development and laboratory ser...
Specialty pharmaceutical company
Appears in
Your company? Embed this profile
Add the live badge to your site — it stays current as your funding data updates.
<a href="https://indexed.vc/companies/alpheus-medical"><img src="https://indexed.vc/api/badge/company/alpheus-medical" alt="Alpheus Medical on Indexed.vc" width="260" height="76" /></a>