All Rankings

Top 100 AI Startups in New York City 2026

The most-funded artificial intelligence and machine learning startups headquartered in New York City, ranked by total capital raised.

Known total funding for 100 of 100 ranked companies: $32.1B.

Showing top 100 matching companies · Ranked by total funding raised

Use company data through the API.
Example request
curl "https://indexed.vc/api/v1/companies?industries=Artificial+Intelligence,Generative+AI,Machine+Learning&countries=United+States&cities=New+York+City,New+York&operatingStatus=active&sort=total_funding_raised&order=desc&limit=100" -H "X-API-Key: YOUR_API_KEY"

The API has no company type filter, so public companies can appear; this list counts private companies only.

The API cannot leave out companies whose latest round is a grant, private equity or debt financing; this list does.

Data from Indexed.vcUpdated

Methodology: up to 100 active companies matching this list's filters are ordered by disclosed total funding in USD. Companies whose latest round is one of: Grant, Private Equity, Debt Financing are excluded. Totals include recorded grants and other qualifying funding, not just equity. Open a company profile for its funding summary and available detail. How this data is built.

26
Cadence

Cadence helps health systems deliver continuous chronic care through clinical AI, remote monitori...

New York, United States201–500Life Sciences, Healthcare
Series CTotal funding$344.0MJun 2026
27
Redesign Health

Venture and applied-technology firm that builds and funds healthcare startups, partnering with fo...

New York, United States51–200Life Sciences, Artificial Intelligence
Venture RoundTotal funding$340.0MDec 2024
28
Deep Instinct

Preemptive cybersecurity company using deep learning to prevent and explain unknown zero-day thre...

New York, United States201–500Artificial Intelligence, Cybersecurity
Venture RoundTotal funding$333.7MSep 2022
29
ASAPP

AI-native platform providing autonomous AI agents for enterprise contact centers, handling custom...

New York, United States201–500Artificial Intelligence, SaaS
Series CTotal funding$332.6MMay 2021
30
Loadsmart

Provides AI-driven logistics and transportation solutions (TMS, brokerage, managed transportation...

New York, United States201–500Artificial Intelligence, Data & Analytics
Series DTotal funding$330.6MFeb 2022
31
Clay

Data enrichment and GTM automation platform that helps sales and marketing teams build targeted p...

New York, United States51–200Artificial Intelligence, Marketing Tech
Series DTotal funding$325.0MSep 2026
32
Altana

AI-powered supply chain network connecting businesses, logistics providers, and governments aroun...

New York, United States201–500Artificial Intelligence, Logistics
Series CTotal funding$301.5MJul 2024
33
Immunai

Immunai maps the immune system using single-cell genomics and ML to accelerate drug discovery and...

New York, United States51–200Artificial Intelligence, Biotech
Series BTotal funding$295.0MOct 2021
34
CertiK

CertiK is a pioneer in blockchain security, utilizing best-in-class AI technology to secure and m...

New York, United States201–500Artificial Intelligence, Crypto & Web3
Series BTotal funding$292.5MApr 2022
35
Queen of Raw

Queen of Raw is a global marketplace w/AI-powered supply chain software to eliminate and monetize...

New York, United States11–50IoT, Artificial Intelligence
Venture RoundTotal funding$289.5MNov 2022
36
Ontra Mobility

Ontra provides transit agencies with connected software for network planning, service operations,...

New York, United States1–10Artificial Intelligence, Climate Tech
Series BTotal funding$270.0MOct 2021
37
Norm Ai

AI platform converting regulations and corporate policies into executable compliance agents super...

New York, United States51–200Artificial Intelligence, SaaS
Series DTotal funding$256.1MJun 2026
38
Savvy Wealth

Digital-first wealth management platform partnering with independent financial advisors to delive...

New York, United States51–200Artificial Intelligence, Financial Services
Series CTotal funding$249.5MSep 2026
39
doubleAI

doubleAI is developing AI systems intended to surpass expert-level capabilities in science and te...

New York, United States11–50Artificial Intelligence, Generative AI
Series ATotal funding$241.0MSep 2025
40
Sentra

Cloud-native data security posture management (DSPM) platform helping enterprises secure AI adopt...

New York, United States51–200Artificial Intelligence, Cybersecurity
Series CTotal funding$240.0MNov 2026
41
BigID

Enterprise data security, privacy, compliance, and governance platform enabling organizations to ...

New York, United States201–500Artificial Intelligence, Cybersecurity
Series DTotal funding$226.1MNov 2025
42
Captions

Captions is an AI video editor that automatically cuts scenes, overlays B-roll, and generates cap...

New York, United States51–200Artificial Intelligence, Media
Growth EquityTotal funding$210.0MMar 2026
43
Hyperscience

Hyperscience builds an agentic AI platform that reads, understands, and processes documents at ma...

New York, United States201–500Artificial Intelligence, Automation
Series ETotal funding$210.0MDec 2021
44
Smartling

Cloud-based AI-powered translation and localization platform that helps enterprises translate and...

New York, United States201–500Artificial Intelligence, SaaS
Growth EquityTotal funding$209.0MDec 2021
45
Rillet

Rillet is an AI-native ERP designed by accountants to automate general ledger, close, and reporti...

New York, United States51–200Artificial Intelligence, Fintech
Series CTotal funding$208.5MAug 2026
46
Inspiren

Founded in 2016 by former Green Beret and cardiothoracic nurse Michael Wang, Inspiren is senior l...

New York, United States51–200Artificial Intelligence, Healthcare
Series CTotal funding$205.0MSep 2026
47
VidMob

Creative intelligence platform

New York, United States51–200Artificial Intelligence, SaaS
Series DTotal funding$194.5MAug 2022
48
Reserv

Reserv is an AI-native third-party administrator that automates property and casualty insurance c...

New York, United States201–500Artificial Intelligence, Insurtech
Series CTotal funding$194.0MMay 2026
49
OpenRouter

OpenRouter is a unified AI gateway offering developers a single API to access 500+ models from 80...

New York, United States1–10Infrastructure, Artificial Intelligence
Series BTotal funding$188.0MMay 2026
50
Vega Security

AI-native SecOps platform providing federated security analytics, threat detection, and triage fo...

New York, United States51–200Artificial Intelligence, Cybersecurity
Series ATotal funding$185.0MMar 2026