Pillar VC
Venture Capital
Boston-based pre-seed and seed VC. Pre-seed investments $50K-$500K, seed rounds $2-6M.
Boston, United States · 39+ investments · 86 portfolio companies
Pre-Seed
Seed
Biotech
Crypto & Web3
Fintech
Advanced Computing
Artificial Intelligence
Deep Tech
Healthcare
- Headquarters
- Boston, United States
- Founded
- 2016
- Website
- pillar.vc
- AUM
- $500.0M
- Portfolio Companies
- 86
- Total Investments
- 39
- Last Investment
- Jan 2026
- Geographic Focus
- Boston, United States
Investment Thesis
Pre-seed and seed VC partnering with technically brilliant founders at inception, with a focus on university spinouts and academic researchers in Boston and beyond, supported by a community of 32 founding CEO pillars.
Pillar VC is a Venture Capital firm based in Boston, United States. It has made 39 investments in Biotech and Crypto & Web3, including Refraction AI, VideaHealth and LightSource AI.
Portfolio86
RA
Refraction AILA
LightSource AI
DB
Drosera BioS
Shopped
M
Mirian
AE
Ayo Electronics
T
TezzaA(
AnyQuestion (Whoop)
M
Mesoware
M
Matterworks
SX
Sphere X
Co-investors24
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24 co-investors across 88 shared portfolio companies — who they back alongside, and how often they lead.
Venture Capital ×21 · Accelerator ×1 · Hedge Fund ×1 · 30 shared rounds
Investment History
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