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Top DeFi Companies

70 DeFi companies, sorted by total funding raised.

LumenaClosed

Lumena Pharmaceuticals is developing oral therapeutics for rare liver diseases to improve liver f...

DeFi, Real-world assets
Series A·$8.0M·Jun 2025
Runloop

Builds DeFi simulation environments and trains autonomous agents to provide liquidity, manage ris...

San Francisco, United States1–10Crypto & Web3, Artificial Intelligence
Seed·$7.0M·Jul 2025
Azura

On-chain trading platform enabling users to trade across multiple blockchains with non-custodial ...

New York City, United States1–10Crypto & Web3, DeFi
Seed·$6.9M·Oct 2024
OnRe

DeFi lending protocol.

Hamilton, Bermuda11–50Crypto & Web3, DeFi
Venture Unknown·$6.9M·May 2026
neverless

Providing democratised access to decentralised finance, by addressing the complexity, high fees a...

Berlin, GermanyCrypto & Web3, DeFi
Venture Unknown·$6.7M·Aug 2024
SensibleAcquired

High yield account for crypto.

New York, United States1–10Crypto & Web3, Fintech
Seed·$6.5M·Oct 2023
Seashells

Web3 venture studio and DeFi savings platform supporting the decentralized financial ecosystem.

Las Vegas, United States11–50Fintech, DeFi
Seed·$6.0M·Jan 2022
Reflexer Labs

Stablecoin protocol

San Francisco, United States1–10Crypto & Web3, DeFi
Series A·$5.8M·Feb 2021
AngleClosed

Angle Protocol focus on offering stablecoins pegged to currencies like the euro as an alternative...

San Francisco, United States11–50Crypto & Web3, DeFi
Seed·$5.0M·Sep 2021
Cypher

Banking built with on-chain primitives for web3 founders and teams

Palo Alto, United States1–10DeFi, Payments
Seed·$4.3M·Jan 2023
CashmereClosed

Crypto wallet for web3 startups

San Francisco, United States1–10Crypto & Web3, DeFi
Seed·$3.6M·Aug 2022
Ampleforth

Decentralized, supply-elastic cryptocurrency protocol (AMPL) that targets a CPI-adjusted dollar, ...

San Francisco, United States1–10Crypto & Web3, DeFi
Seed·$3.0M·Mar 2018
Kairos Labs

DeFi protocol and liquidity infrastructure startup.

New York, United States1–10Crypto & Web3, DeFi
Seed·$2.4M·Apr 2026
EthosX

The protocol for derivatives on blockchains

Claymont, United States1–10DeFi, Crypto & Web3
Venture Unknown·$2.3M·Aug 2022
HedgehogClosed

Cryptocurrency Robo-adviser. Buy. Balance. Relax.

San Jose, United States1–10DeFi, Crypto & Web3
Seed·$1.6M·Aug 2021
Multipli

ZK-based multi-chain yield protocol enabling yield on stablecoins, native assets, and non-yield-b...

1–10Crypto & Web3, DeFi
Seed·$1.5M
MVX

An Austin and Lagos-based software company simplifying global trade for businesses in emerging ma...

San Francisco Bay Area, NigeriaSupply Chain, Crypto & Web3
Seed·$1.4M·Aug 2021
PayfuraClosed

Global payment gateway to buy/sell crypto

Delaware City, United States1–10DeFi, SaaS
Pre-seed·$500K·Jun 2022
Flux

Cross border Payments infrastructure for internet businesses and…

Mexico City, Mexico1–10DeFi, Crypto & Web3
Seed·$150K·Aug 2019
PrimeVault

Supercharged crypto operations, custody and risk management

San Francisco, United States1–10Crypto & Web3, DeFi
Seed·$125K·Jul 2022
Parallel Finance

Decentralized finance (DeFi) protocol on the Polkadot ecosystem offering lending, staking, tradin...

San Francisco, United States51–200Crypto & Web3, DeFi
Series A·Aug 2021
CoW Protocol

Decentralized meta-DEX swap protocol using intent-based batch auctions to protect users from MEV ...

DeFi, Crypto & Web3
Funding undisclosed
Blume (Bunker.finance)

NFT backed loans

Developer Tools, NFT
Funding undisclosed
F
FeiAcquired

Decentralized algorithmic stablecoin protocol using Protocol Controlled Value (PCV) to maintain a...

DeFi, Crypto & Web3
Funding undisclosed
Mirror Protocol

Decentralized finance protocol enabling synthetic assets that track real-world asset prices on Te...

Crypto & Web3, DeFi
Funding undisclosed