Soufflé Therapeutics
Redefining how medicines are made
Watertown, United States · Founded 2024 · $271.6M raised
- Headquarters
- Watertown, Massachusetts
- Employees
- 51–200
- Founded
- 2024
- Business Model
- B2B
- Website
- souffletx.com
- Total Funding
- $271.6M
- Last Round
- $200.0M Series AOct 2025
- Rounds
- 2
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
Indexed holds 2 funding rounds and 3 investors for this company. The full record is or through the API.
About
Soufflé Therapeutics is a Watertown, Massachusetts-based biotechnology company founded by pioneers in genetic medicine including MIT professors Robert Langer and Daniel Anderson, along with Victor Kotelianski and Marino Zerial. The company engineers cell-specific ligands to deliver siRNA-based medicines that are precise, potent, and transferred across the cell membrane to their target. Soufflé combines proprietary technologies for cell-specific receptor identification, ligand optimization, and siRNA engineering to create safer, stronger, and more durable medicines. Its first programs target Facioscapulohumeral Muscular Dystrophy (FSHD) and genetically-driven cardiomyopathies, with clinical trials planned for 2026. The company emerged from stealth in October 2025 with $200M in Series A financing and has executed over $3.5B in capital raised and collaboration agreements with pharma partners including Bayer, AbbVie, Amgen, and Novo Nordisk.
Summary
Soufflé Therapeutics is a Biotech company based in Watertown, United States, founded in 2024. It has raised $271.6M in total across 2 rounds, most recently a $200.0M Series A round in Oct 2025. Investors include Bessemer Venture Partners, Leaps by Bayer and Polaris Partners.
Tech & App Stack
3 technologies & apps tracked
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Funding History
Oct 2025
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Funding: Seed through Series A. Amounts, valuations, and investors where available.
Investors
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