Protego Bio

First-in-Class Therapies for Protein Misfolding Diseases

Protego Bio is headquartered in San Diego, United States, lists 1–10 employees, and has $181.0M in recorded funding across 2 rounds.

Headquarters
San Diego
Employees
1–10
Business Model
B2B
Total Funding
$181.0M
Last Round
$130.0M Series BDec 2025
Rounds
2

Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.

Indexed holds 2 funding rounds and 6 investors for this company. The full record is or through the API.

About

Protego Bio is a clinical-stage biotech headquartered in San Diego that develops first-in-class small molecule pharmacological chaperones to treat protein misfolding diseases such as AL amyloidosis. The company was co-founded by Dr. Jeffery W. Kelly and Dr. Richard Labaudinière, who previously led the discovery of tafamidis, the first disease-modifying therapy for transthyretin amyloidosis. Protego Bio's lead candidate, PROT-001, is designed to stabilize misfolded light chain proteins and is advancing toward pivotal studies for AL amyloidosis, backed by $181 million raised across Series A and Series B financing.

Summary

Protego Bio is a Biotech company based in San Diego, United States. It lists 1–10 employees. It has raised $181.0M in total across 2 rounds, most recently a $130.0M Series B round in Dec 2025. Investors include Lightspeed Venture Partners, MPM BioImpact and Novartis Venture Fund.

Tech & App Stack

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Funding History

Series BSeries BDec 2025
$130.0M

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Funding: Series A through Series B. Amounts, valuations, and investors where available.

Investors

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