Protego Bio
First-in-Class Therapies for Protein Misfolding Diseases
San Diego, United States · $181.0M raised
- Headquarters
- San Diego
- Employees
- 1–10
- Business Model
- B2B
- Website
- protegobio.com
- Total Funding
- $181.0M
- Last Round
- $130.0M Series BDec 2025
- Rounds
- 2
About
Protego Bio is a clinical-stage biotech headquartered in San Diego that develops first-in-class small molecule pharmacological chaperones to treat protein misfolding diseases such as AL amyloidosis. The company was co-founded by Dr. Jeffery W. Kelly and Dr. Richard Labaudinière, who previously led the discovery of tafamidis, the first disease-modifying therapy for transthyretin amyloidosis. Protego Bio's lead candidate, PROT-001, is designed to stabilize misfolded light chain proteins and is advancing toward pivotal studies for AL amyloidosis, backed by $181 million raised across Series A and Series B financing.
Summary
Protego Bio is a Biotech company based in San Diego, United States. It has raised $181.0M in total across 2 rounds, most recently a $130.0M Series B round in Dec 2025. Investors include Lightspeed Venture Partners, MPM BioImpact and Novartis Venture Fund.
Tech & App Stack
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Funding History
Dec 2025
Sign up to see all 2 rounds
Series A through Series B — per-round amounts, valuations, and who invested in each round.
Investors
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