Prolific Machines
Illuminating biomanufacturing. Enabling tomorrow's biotherapeutics.
Prolific Machines was founded in 2020, is headquartered in San Francisco, United States, lists 11–50 employees, and has $97.0M in recorded funding across 4 rounds.
- Headquarters
- San Francisco, California
- Employees
- 11–50
- Founded
- 2020
- Business Model
- B2B
- Website
- prolific-machines.com
- Total Funding
- $97.0M
- Last Round
- $55.0M Series BJun 2024
- Rounds
- 4
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
Indexed holds 4 funding rounds and 4 investors for this company. The full record is or through the API.
About
Prolific Machines is a biotechnology company pioneering optogenetic cell line development and AI-driven bioprocess optimization for biopharmaceutical manufacturing. The company's Photomolecular platform uses light to precisely control gene expression in mammalian cell lines, enabling up to 5-fold increases in therapeutic protein titers and unlocking production of difficult-to-express biotherapeutics including antibodies, biosimilars, and multispecific proteins. By decoupling cell growth from protein production through light-mediated control, Prolific addresses key challenges in biomanufacturing cost, consistency, and scalability. The platform is cell-line agnostic and adaptable to any bioreactor, positioning it as an infrastructure layer for next-generation biologics production.
Summary
Prolific Machines is a Biotech company based in San Francisco, United States, founded in 2020. It lists 11–50 employees. It has raised $97.0M in total across 4 rounds, most recently a $55.0M Series B round in Jun 2024. Investors include Mayfield Fund, Breakthrough Energy Ventures and Ki Tua Fund.
Tech & App Stack
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Funding History
Jun 2024
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Funding: Pre-Seed through Series B. Amounts, valuations, and investors where available.
Investors
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