Lewis & Clark Ventures

Venture Capital

We invest in B2B SaaS with $1M+ ARR

St. Louis, United States · 9+ investments · 8 portfolio companies

Seed
Early Stage
Headquarters
St. Louis, United States
Founded
2015
Portfolio Companies
8
Total Investments
9
Last Investment
Oct 2025
Geographic Focus
United States, Midwest

Investment Thesis

We invest in B2B SaaS with $1M+ ARR

Lewis & Clark Ventures is a Venture Capital firm based in St. Louis, United States. It has made 9 investments, including Amper, Plastomics and Splento.

Portfolio8

Co-investors24

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24 co-investors across 24 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×19 · Accelerator ×2 · Angel Group ×1 · 18 shared rounds

Investment History

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