Raleigh-based family office founded by entrepreneur Bill Spruill, investing in early-stage startups.

Raleigh, United States · 5+ investments · 5 portfolio companies

Pre-Seed
Seed
Early Stage
Biotech
Media
Headquarters
Raleigh, United States
Founded
2022
Website
2ndf.org
Portfolio Companies
5
Total Investments
5
Last Investment
Oct 2025
Geographic Focus
United States

Investment Thesis

Angel and early-stage investing to advance minority education programs and tech sector growth.

2ndF is a Venture Capital firm based in Raleigh, United States. It has made 5 investments in Biotech and Media, including AI or Not, NATRX INC and iOrgan Bio.

Portfolio5

Co-investors17

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17 co-investors across 18 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×13 · Accelerator ×4 · 10 shared rounds

Investment History

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