Profluent
formerly Profluent BioProgramming biology with AI
Berkeley, United States · Founded 2022 · $150.0M raised
- Headquarters
- Berkeley, California
- Employees
- 11–50
- Founded
- 2022
- Business Model
- B2B
- Website
- profluent.bio
- Total Funding
- $150.0M
- Last Round
- $106.0M Series BNov 2025
- Rounds
- 3
About
Profluent is a frontier AI company based in Berkeley applying deep generative models to protein design. ProGen models trained on billions of protein sequences enable programmable biology for drug development, gene editing, and industrial biotech. Created OpenCRISPR, the first AI-designed gene editor. Founded 2022.
Summary
Profluent is a Life Sciences company based in Berkeley, United States, founded in 2022. It has raised $150.0M in total across 3 rounds, most recently a $106.0M Series B round in Nov 2025. Investors include Insight Partners, Air Street Capital and AIX Ventures.
Tech & App Stack
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Funding History
Nov 2025
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Seed through Series B — per-round amounts, valuations, and who invested in each round.
Investors
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