Affinia Therapeutics

Expanding what's possible in AAV gene therapy today.

Waltham, United States · Founded 2019 · $210.0M raised

Employees
51–200
Founded
2019
Business Model
B2B
Total Funding
$210.0M
Last Round
$40.0M Series COct 2025
Rounds
3

About

Affinia Therapeutics pioneers rationally designed AAV gene therapies for rare and prevalent diseases, focusing on heart and nervous system disorders. Using AI and structural modeling, their ART platform creates novel capsids for improved tissue targeting, safety, and efficacy. Their lead program AFTX-201 targets BAG3-associated dilated cardiomyopathy.

Summary

Affinia Therapeutics is a Biotech company based in Waltham, United States, founded in 2019. It has raised $210.0M in total across 3 rounds, most recently a $40.0M Series C round in Oct 2025. Investors include New Enterprise Associates, F-Prime Capital and EcoR1 Capital.

Tech & App Stack

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Funding History

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Series CSeries COct 2025
$40.0M

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Series A through Series C — per-round amounts, valuations, and who invested in each round.

Investors

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