Adnexus Therapeutics

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Pioneering Adnectin therapeutics based on human fibronectin.

Waltham, United States · Founded 2003 · $42.5M raised

Employees
1–10
Founded
2003
Business Model
B2B
Total Funding
$42.5M
Last Round
$15.5M Series CAug 2007
Rounds
2

About

Adnexus Therapeutics, founded in 2003 and headquartered in Waltham, Massachusetts, was a biopharmaceutical company that pioneered Adnectin therapeutics — engineered variants of the tenth type III domain of human fibronectin. Adnectins were designed as a new protein scaffold platform to generate highly potent, specific, and stable therapeutic agents with favorable half-life and high-yield E. coli production. The company's lead oncology compound, CT-322, was an Adnectin inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) developed as an anti-angiogenic cancer therapy. Adnexus was founded by Flagship Pioneering (then Flagship Ventures) and acquired by Bristol-Myers Squibb in September 2007 for approximately $430 million, making it one of the largest biotech acquisitions of that year.

Summary

Adnexus Therapeutics is a Biotech company based in Waltham, United States, founded in 2003. It has raised $42.5M in total across 2 rounds, most recently a $15.5M Series C round in Aug 2007. Investors include Bristol Myers Squibb, HBM BioVentures and Venrock.

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Funding History

AcquisitionAcquisition by Bristol-Myers SquibbSep 2007
$430.0M

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