Wireframe Ventures

Venture Capital

$77M Fund II. Portfolio includes Mammoth Biosciences, SPAN.io, MycoWorks.

Mill Valley, United States · 27+ investments · 22 portfolio companies

Pre-Seed
Seed
Climate Tech
Healthcare
Clean Tech
Sustainability
Headquarters
Mill Valley, United States
Founded
2016
AUM
$50.0M
Portfolio Companies
22
Total Investments
27
Last Investment
Jul 2025
Geographic Focus
United States

Indexed holds 22 portfolio companies and 27 funding rounds for this investor. The full record is or through the API.

Investment Thesis

We invest in extraordinary seed-stage founders on a mission to improve the health of people and planet. We focus on technology companies across climate, biotech, healthcare, and sustainability — backing founders from the very first check through their Series A and beyond.

Wireframe Ventures is a Venture Capital firm based in Mill Valley, United States. It has made 27 investments, including Bedrock Energy, Xcimer and Sora Fuel. Focus areas include Climate Tech and Healthcare.

Portfolio22

Co-investors24

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24 co-investors across 49 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×19 · Accelerator ×4 · Corporate VC ×1 · 40 shared rounds

Investment History

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Wireframe Ventures on Indexed.vc
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