
Wireframe Ventures
Venture Capital
$77M Fund II. Portfolio includes Mammoth Biosciences, SPAN.io, MycoWorks.
Pre-Seed
Seed
Climate Tech
Healthcare
Clean Tech
Sustainability
- Headquarters
- Mill Valley, United States
- Founded
- 2016
- Website
- wireframevc.com
- AUM
- $50.0M
- Total Investments
- 20
- Last Investment
- Jul 2025
- Geographic Focus
- United States
Investment Thesis
We invest in extraordinary seed-stage founders on a mission to improve the health of people and planet. We focus on technology companies across climate, biotech, healthcare, and sustainability — backing founders from the very first check through their Series A and beyond.
Investment History
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