Wireframe Ventures

Venture Capital

$77M Fund II. Portfolio includes Mammoth Biosciences, SPAN.io, MycoWorks.

Pre-Seed
Seed
Climate Tech
Healthcare
Clean Tech
Sustainability
Headquarters
Mill Valley, United States
Founded
2016
AUM
$50.0M
Total Investments
20
Last Investment
Jul 2025
Geographic Focus
United States

Investment Thesis

We invest in extraordinary seed-stage founders on a mission to improve the health of people and planet. We focus on technology companies across climate, biotech, healthcare, and sustainability — backing founders from the very first check through their Series A and beyond.

Investment History

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