Wireframe Ventures

Venture Capital

$77M Fund II. Portfolio includes Mammoth Biosciences, SPAN.io, MycoWorks.

Mill Valley, United States · 28+ investments · 23 portfolio companies

Pre-Seed
Seed
Climate Tech
Healthcare
Clean Tech
Sustainability
Headquarters
Mill Valley, United States
Founded
2016
AUM
$50.0M
Portfolio Companies
23
Total Investments
28
Last Investment
Jul 2025
Geographic Focus
United States

Investment Thesis

We invest in extraordinary seed-stage founders on a mission to improve the health of people and planet. We focus on technology companies across climate, biotech, healthcare, and sustainability — backing founders from the very first check through their Series A and beyond.

Wireframe Ventures is a Venture Capital firm based in Mill Valley, United States. It has made 28 investments in Climate Tech and Healthcare, including Bedrock Energy, Xcimer and Sora Fuel.

Portfolio23

Co-investors24

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24 co-investors across 50 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×20 · Accelerator ×3 · Corporate VC ×1 · 43 shared rounds

Investment History

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