S3 Ventures

Venture Capital

Largest venture capital firm born in Texas, leading Seed, Series A, and Series B rounds in business software and healthcare technology.

Early Stage
Growth
Healthcare
SaaS
Headquarters
Austin, United States
Founded
2005
Website
s3vc.com
AUM
$1.0B
Portfolio Company
1
Total Investments
21
Last Investment
Mar 2026
Geographic Focus
United States

Investment Thesis

Lead Seed through Series B rounds in business software and healthcare technology companies, backed by a single LP enabling patient, flexible capital without fundraising distractions.

Portfolio1

Investment History

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S3 Ventures: Investor Profile & Portfolio | Indexed.vc