S3 Ventures

Venture Capital

Largest venture capital firm born in Texas, leading Seed, Series A, and Series B rounds in business software and healthcare technology.

Austin, United States · 64+ investments · 77 portfolio companies

Early Stage
Growth
Healthcare
SaaS
Headquarters
Austin, United States
Founded
2005
Website
s3vc.com
AUM
$1.0B
Portfolio Companies
77
Total Investments
64
Last Investment
Aug 2026
Geographic Focus
United States

Investment Thesis

Lead Seed through Series B rounds in business software and healthcare technology companies, backed by a single LP enabling patient, flexible capital without fundraising distractions.

S3 Ventures is a Venture Capital firm based in Austin, United States. It has made 64 investments in Healthcare and SaaS, including LibreDigital, Kimbia and Briggo.

Portfolio77

Co-investors24

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24 co-investors across 64 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×20 · Accelerator ×1 · Private Equity ×1 · 35 shared rounds

Investment History

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