S3 Ventures is a Venture Capital based in Austin.

How many investments has S3 Ventures made?

S3 Ventures has made 65 disclosed investments.

How much does S3 Ventures manage?

S3 Ventures manages $1.0B in assets.

What does S3 Ventures invest in?

S3 Ventures invests in Healthcare, SaaS Early Stage, Growth companies.

What companies has S3 Ventures invested in?

S3 Ventures's portfolio includes LibreDigital, Kimbia, Briggo, Cloverleaf AI, Crogl, Acessa Health.

S3 Ventures

Venture Capital

Largest venture capital firm born in Texas, leading Seed, Series A, and Series B rounds in business software and healthcare technology.

Austin, United States · 65+ investments · 78 portfolio companies

Website

Early Stage

Growth

Healthcare

SaaS

Headquarters: Austin, United States
Founded: 2005
Website: s3vc.com
AUM: $1.0B

Portfolio Companies: 78
Total Investments: 65
Last Investment: Aug 2026
Geographic Focus: United States

Indexed holds 78 portfolio companies and 65 funding rounds for this investor. The full record is or through the API.

Investment Thesis

Lead Seed through Series B rounds in business software and healthcare technology companies, backed by a single LP enabling patient, flexible capital without fundraising distractions.

S3 Ventures is a Venture Capital firm based in Austin, United States. It has made 65 investments, including LibreDigital, Kimbia and Briggo. Focus areas include Healthcare and SaaS.

Portfolio78

Showing 48 of 78 recorded portfolio companies.

Co-investors24

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24 co-investors across 62 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×18 · Accelerator ×3 · Corporate VC ×1 · 31 shared rounds

Investment History

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