S3 Ventures is a Venture Capital based in Austin.

How many investments has S3 Ventures made?

S3 Ventures has made 36 disclosed investments.

How much does S3 Ventures manage?

S3 Ventures manages $1.0B in assets.

What does S3 Ventures invest in?

S3 Ventures invests in Healthcare, SaaS Early Stage, Growth companies.

What companies has S3 Ventures invested in?

S3 Ventures's portfolio includes Arpio.

S3 Ventures

Venture Capital

Largest venture capital firm born in Texas, leading Seed, Series A, and Series B rounds in business software and healthcare technology.

Austin, United States · 36+ investments · 1 portfolio companies

Website

Early Stage

Growth

Healthcare

SaaS

Headquarters: Austin, United States
Founded: 2005
Website: s3vc.com
AUM: $1.0B

Portfolio Company: 1
Total Investments: 36
Last Investment: Mar 2026
Geographic Focus: United States

Investment Thesis

Lead Seed through Series B rounds in business software and healthcare technology companies, backed by a single LP enabling patient, flexible capital without fundraising distractions.

S3 Ventures is a Venture Capital firm based in Austin, United States. It has made 36 investments in Healthcare and SaaS, including Arpio.

Portfolio1

Arpio

Investment History

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