S3 Ventures is the largest and longest-serving venture capital firm born in Texas, investing nationwide in business software and healthcare technology since 2005. Backed by a single philanthropic family, it typically leads seed through Series B rounds with $500K-$10M checks.
Austin, United States · 1+ investments · 1 portfolio companies
- Headquarters
- Austin, United States
- Founded
- 2005
- Website
- s3vc.com
- AUM
- $1.0B
- Portfolio Company
- 1
- Total Investment
- 1
- Last Investment
- Jul 2026
- Geographic Focus
- United States
Indexed holds 1 portfolio company and 1 funding round for this investor. The full record is or through the API.
Investment Thesis
S3 is a Venture Capital firm based in Austin, United States. It has made 1 investment, including Vendelux. Focus areas include Digital Health and SaaS.
Portfolio1
Co-investors10
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10 co-investors across 10 shared portfolio companies — who they back alongside, and how often they lead.
Venture Capital ×10 · 1 shared rounds
Investment History
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