Nantahala Capital

Hedge Fund

Fundamentally-driven alternative investment firm founded in 2004, focusing on micro-cap stocks with market-neutral long/short strategies.

New Canaan, United States · 4+ investments · 3 portfolio companies

Healthcare
Headquarters
New Canaan, United States
Founded
2004
AUM
$2.3B
Portfolio Companies
3
Total Investments
4
Last Investment
Aug 2025
Geographic Focus
United States

Investment Thesis

Maximize risk-adjusted returns via diversified portfolio of long/short ideas in micro-caps with low market beta.

Nantahala Capital is a Hedge Fund firm based in New Canaan, United States. It has made 4 investments in Healthcare, including Fractyl Health, Senti Biosciences and Trisalus Life Sciences.

Portfolio3

Co-investors24

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24 co-investors across 24 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×17 · Corporate VC ×3 · Hedge Fund ×2 · 8 shared rounds

Investment History

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