Main Sequence Ventures

Venture Capital

We invest in founders building the next generation of global industries by leveraging deep...

Sydney, Australia · 29+ investments · 17 portfolio companies

Seed
Early Stage
Artificial Intelligence
Biotech
decarbonisation
Deep Tech
Healthcare
Space Tech
Headquarters
Sydney, Australia
Founded
2017
Website
mseq.vc
AUM
$1.0B
Portfolio Companies
17
Total Investments
29
Last Investment
Apr 2026
Geographic Focus
Australia

Investment Thesis

We invest in founders building the next generation of global industries by leveraging deep...

Main Sequence Ventures is a Venture Capital firm based in Sydney, Australia. It has made 29 investments, including Cauldron, Kasada and RIOS. Focus areas include Artificial Intelligence and Biotech.

Portfolio17

Co-investors24

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24 co-investors across 39 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×18 · Sovereign Wealth Fund ×2 · Other ×1 · 46 shared rounds

Investment History

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