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25Madison

Venture Capital

25madison is a venture and innovation platform that co-founds and invests in AI-native and tech-enabled businesses from pre-seed to Series A, focused on B2B software and healthcare.

New York, United States · 10+ investments · 9 portfolio companies

Pre-Seed
Seed
Fintech
Healthcare
Supply Chain
Headquarters
New York, United States
Website
25madison.com
Portfolio Companies
9
Total Investments
10
Last Investment
Apr 2026

Investment Thesis

Invests pre-seed to Series A in category-defining B2B SaaS startups in fintech, healthcare, supply chain with strategic guidance.

25Madison is a Venture Capital firm based in New York, United States. It has made 10 investments, including Kyra Health, Silkline and Rebuild. Focus areas include Fintech and Healthcare.

Portfolio9

Co-investors24

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24 co-investors across 24 shared portfolio companies — who they back alongside, and how often they lead.

Venture Capital ×22 · Angel Group ×2 · 26 shared rounds

Investment History

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